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Mashup Score: 8Secretory IgA: controlling the gut microbiota - Nature Reviews Gastroenterology & Hepatology - 4 year(s) ago
Secretory immunoglobulin A (SIgA) regulates the composition and function of the gut microbiota and modulates its interaction with the host, but how this regulation is achieved is poorly understood. Now, Rollenske and colleagues profile the consequences of SIgA binding to the gut microbiota. They suggest that parallel generic and unique epitope-specific effects of SIgA regulate the intestinal…
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Mashup Score: 2Gut microbiome and autism spectrum disorder - Nature Reviews Gastroenterology & Hepatology - 4 year(s) ago
Nature Reviews Gastroenterology & Hepatology –
Gut microbiome and autism spectrum… Categories: Gastroenterology, Latest HeadlinesTweet-
New content online: Gut microbiome and autism spectrum disorder https://t.co/XTNzY0BFOY https://t.co/2BCId8NGhx
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Mashup Score: 0The global burden of IBD: from 2015 to 2025 - Nature Reviews Gastroenterology & Hepatology - 4 year(s) ago
IBD is a chronic, incurable disease and can be a major burden to health-care resources. Moreover, the epidemiology of IBD is changing worldwide. In this Perspectives, Gilaad Kaplan discusses the current global burden of IBD and how this might evolve over the next decade, as well as the challenges that might arise with this changing incidence.
Categories: Gastroenterology, Latest HeadlinesTweet-
#TrendingNow *IBD 2015-2025 https://t.co/lOUuyNyubM *Prebiotics https://t.co/qCukju128M *NAFLD pipeline https://t.co/RqJhtb5LwY *Mycobiota https://t.co/Jbu3uZsr6o https://t.co/EUjU6nqYuI
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Mashup Score: 29Therapeutic pipeline in nonalcoholic steatohepatitis - Nature Reviews Gastroenterology & Hepatology - 4 year(s) ago
The therapeutic pipeline for nonalcoholic steatohepatitis (NASH) is expanding as insights into disease pathophysiology are gained. This Review summarizes progress in the development of NASH therapies, current and ongoing clinical trials, and potential challenges with emerging therapies.
Categories: Hem/Oncs, Latest HeadlinesTweet-
Principales causas de morbilidad y mortalidad en varios subfenotipos de enfermedad del hígado graso no alcohólico: DOI: https://t.co/wpxEw0cCzO https://t.co/ET6RbAxJN8
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Mashup Score: 2Mycobiota–host immune interactions in IBD: coming out of the shadows - Nature Reviews Gastroenterology & Hepatology - 4 year(s) ago
2021 has been a productive year for fungal research. Key studies focused on intestinal inflammation and inflammatory bowel disease highlight antibody-mediated immunity in control of fungal commensalism, commensal and dietary fungi in intestinal inflammation and wound healing, and the therapeutic potential of transgenic yeast engineered to sense and target factors during intestinal inflammation.
Categories: Gastroenterology, Latest HeadlinesTweet-
#YearinReview | GUT MICROBIOTA IN 2021 #Mycobiota–host immune interactions in #IBD: coming out of the shadows https://t.co/Jbu3uZsr6o https://t.co/a93f8qvGcv
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Mashup Score: 1
Cancer development is a dynamic evolutionary process. This Review explores the mechanisms underlying clonal expansion and contraction as well as the evolutionary dynamics in Barrett oesophagus and its progression to dysplasia and oesophageal adenocarcinoma. The implications for patient management (including surveillance, risk stratification and therapy) are also explored.
Categories: Gastroenterology, Latest HeadlinesTweet-
REVIEW | Evolutionary dynamics in Barrett #oesophagus: implications for surveillance, risk stratification and therapy https://t.co/ohh882qpEK https://t.co/HJT8H5DIJX
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Mashup Score: 2Precision medicine in IBD: genes, drugs, bugs and omics - Nature Reviews Gastroenterology & Hepatology - 4 year(s) ago
Key studies published in 2021 demonstrated mechanisms that drive macrophage–fibroblast pathogenicity in Crohn’s disease, developed multi-omics profiles to predict response to biological therapy, and suggested potential complementary treatments and new therapeutic agents in inflammatory bowel disease (IBD) therapy. These results represent important progress towards precision medicine for patients…
Categories: Gastroenterology, Latest HeadlinesTweet-
#YearinReview: IBD in 2021 Precision medicine in #IBD: genes, drugs, bugs and omics https://t.co/qrCndUnrPM https://t.co/BA32kg37KY
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Mashup Score: 13Liver ischaemia–reperfusion injury: a new understanding of the role of innate immunity - Nature Reviews Gastroenterology & Hepatology - 4 year(s) ago
In this Review, Kupiec-Weglinski and colleagues describe the roles of macrophages, neutrophils, and platelets in liver ischaemia–reperfusion injury (LIRI) and discuss potential therapeutic strategies for treating LIRI in transplant recipients.
Categories: Gastroenterology, Latest HeadlinesTweet-
New content online: Liver ischaemia–reperfusion injury: a new understanding of the role of innate immunity https://t.co/rqyHmAi5bO https://t.co/PkHPJN8xck
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Mashup Score: 3Disorders of the enteric nervous system — a holistic view - Nature Reviews Gastroenterology & Hepatology - 4 year(s) ago
Although the role of the enteric nervous system in congenital enteric neuropathic disorders is well acknowledged, its role in systemic diseases is less understood. Here, the authors focus on diseases in which the enteric nervous system has so far not been considered to have a major role and on its emerging role in neurodegeneration, cancer and diabetes.
Categories: Gastroenterology, Latest HeadlinesTweet-
#TBT REVIEW | Disorders of the enteric nervous system — a holistic view https://t.co/EwQ4DtdMc9 #neurogastro https://t.co/ur9p7yzfJQ
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Mashup Score: 10Therapeutic pipeline in nonalcoholic steatohepatitis - Nature Reviews Gastroenterology & Hepatology - 4 year(s) ago
The therapeutic pipeline for nonalcoholic steatohepatitis (NASH) is expanding as insights into disease pathophysiology are gained. This Review summarizes progress in the development of NASH therapies, current and ongoing clinical trials, and potential challenges with emerging therapies.
Categories: Gastroenterology, Latest HeadlinesTweet-
#TBT REVIEW | Therapeutic pipeline in nonalcoholic steatohepatitis https://t.co/RqJhtaOa8o #NAFLD #NASH #fattyliver https://t.co/7svdLfPga0
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New content online: Secretory IgA: controlling the gut microbiota https://t.co/nB4T3LNa8R https://t.co/cHacumWRKv