OrthoEvidence is the global online source for high quality and timely Orthopaedic-only evidence-based summaries, pre-appraised by Orthopaedic medical experts.

In this OE Original, we present a meta-analysis comparing the surgical versus non-surgical treatments for Anterior Cruciate Ligament injuries.

We conducted a systematic review and meta-analysis of randomized controlled trials to determine the efficacy and safety of the addition of dexmedetomidine to the usual analgesic agents (bupivacaine, levobupivacaine or ropivacaine) for femoral nerve block versus the usual femoral nerve block alone for postoperative pain control in patients undergoing total knee arthroplasty.

83 elderly patients with femoral neck fractures were randomized to receive a bipolar hip hemiarthroplasty via a direct anterior approach (DAA; n=40) or an anterolateral approach (ALA; n=43). The outcomes of interest included mobility measured with the Barthel Index, pain on a Visual Analog Scale (VAS), and heterotopic ossification occurrence, all measured up to 1 year post-operation. Pain scores in the first 2 weeks were significantly lower in the DAA group compared to the ALA group. While mobility was significantly better on post-operative day 1 in the DAA group, the ALA group showed superior mobility from week 6 to end of follow-up (1 year post-operation). The rate of heterotopic ossification was also significantly higher in the ALA group in the first 3 months post-operation. The results suggest that DAA may provide superior outcomes in the early post-operative phase, particularly with respect to early mobilization and pain scores. However, mobility may be better in the ALA group as

In this OE Original, we present analytic results generated by OE M.I.N.D. platform tools for a clinical topic: PRP versus corticosteroid injection for painful shoulder conditions. An overview of the available evidence profile, meta-analysis results of head-to-head comparison, profile of ongoing studies and most reported characteristics of prior studies are reported.

850 patients with trochanteric fractures were randomized to receive surgical fixation using an intramedullary nail (n=423, Gamma3 Stryker) or a sliding hip screw (n=427). The primary outcome of interest was health-related quality of life, measured using the Euro-QoL 5-Dimensions (EQ-5D) scale. Secondary outcomes of interest included the incidence of revision, rate of healing, adverse events,…