• Mashup Score: 4

    Acute promyelocytic leukemia (APL) has a well-established mechanism and a long-term prognosis that exceeds that of any other acute leukemia. These improving outcomes are due, in part, to all-trans retinoic acid (ATRA) and arsenic trioxide (ATO), two targeted and highly active agents in this disease. However, there remains a considerable morbidity and mortality risk in APL secondary to clinically…

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    • The Coagulopathy of Acute Promyelocytic Leukemia: An Updated Review of Pathophysiology, Risk Stratification, and Clinical Management https://t.co/EPWcELFprI #mdpicancers via @Cancers_MDPI #AML #leusm https://t.co/6wjJmE8CYy

  • Mashup Score: 0

    Since their discovery at the beginning of this millennium, glioma stem cells (GSCs) have sparked extensive research and an energetic scientific debate about their contribution to glioblastoma (GBM) initiation, progression, relapse, and resistance. Different molecular subtypes of GBM coexist within the same tumor, and they display differential sensitivity to chemotherapy. GSCs contribute to tumor…

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    To date, there has been no recent opinion that explores tempeh as a functional food that can improve sports performance. Hence, this opinion article aims to elaborate on recent findings on the potential effect on sports performance of soy-based tempeh. This opinion paper presents updated evidence based on literature reviews about soy-based tempeh and its relationship with sports performance. The…

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    • Soy-Based Tempeh Rich in Paraprobiotics Properties as Functional Sports Food: More Than a Protein Source https://t.co/uhhSRjBLUy

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    Complete atrioventricular block (AVB) is an abnormal heart rhythm resulting from a defect in the cardiac conduction system. Patients with complete AVB are at risk of symptoms ranging from syncope or hypotension to cardiovascular collapse or sudden cardiac death. A reliable animal model of complete AVB is essential for understanding the mechanisms underlying the fatal hemodynamic effects and…

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    • Use of ethanol injections to create a complete atrioventricular block in a rat model | #THIPubs @Abdou77762664 @MehdiRazavi13 @MathewsMakes @YutaoXiWFG | @Surgeries_MDPI https://t.co/XVpvv0rTki

  • Mashup Score: 1

    The clinical evolution of patients infected with the Severe Acute Respiratory Coronavirus type 2 (SARS-CoV-2) depends on the complex interplay between viral and host factors. The evolution to less aggressive but better-transmitted viral variants, and the presence of immune memory responses in a growing number of vaccinated and/or virus-exposed individuals, has caused the pandemic to slowly wane…

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    • 🚨🚨🚨 HOT OFF THE PRESS: Main Risk Factors for Poor Prognosis in #COVID19 and the Implications for Targeted Measures against SARS-CoV-2. Special chapter of hematological malignancies. Don’t miss it #lymsm #leusm #mmsm #bmtsm #hematology #geriheme https://t.co/pSNRjI0GAC

  • Mashup Score: 19

    Glucocorticoids represent frequently recommended and often indispensable immunosuppressant and anti-inflammatory agents prescribed in various medical conditions. Despite their proven efficacy, glucocorticoids bear a wide variety of side effects among which steroid induced hyperglycaemia (SIHG) is among the most important ones. SIHG, potentially causes new-onset hyperglycaemia or exacerbation of…

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    • Guía práctica para el manejo de la hiperglucemia inducida por esteroides en el hospital. J. Clin. Med. 2021; DOI: https://t.co/k1CC5cRPW2 https://t.co/5NdgLS3CHv

  • Mashup Score: 0

    Heated tobacco products (HTPs) produce aerosol using a different mechanism than tobacco cigarettes, leading to lower emissions of some harmful substances, but also of nicotine as reported by some independent studies. Lower nicotine delivery could lead to compensatory puffing when product use does not sufficiently satisfy cravings. Thus, this three-arm crossover study was conducted to characterize…

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    • Iqos and Neo have different nicotine delivery (with Iqos > Neo), yet lower than conventional cigarettes, suggesting a lower addictive potential. Cravings were reduced by all products, despite different nicotine deliveries https://t.co/uvos0Olcae https://t.co/nBIjrdHNsg

  • Mashup Score: 3

    Unlike other human herpesviruses, human herpesvirus 6A and 6B (HHV-6A/B) infection can lead to integration of the viral genome in human chromosomes. When integration occurs in germinal cells, the integrated HHV-6A/B genome can be transmitted to 50% of descendants. Such individuals, carrying one copy of the HHV-6A/B genome in every cell, are referred to as having inherited chromosomally-integrated…

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    • References & resources: https://t.co/tbjhqnsfVH https://t.co/0z4QgG7PMh https://t.co/Z5LoVqLw9N https://t.co/DBMybNIPwg https://t.co/RMuCDf5k2S https://t.co/sOvL8bM3jk https://t.co/C4bNJ5CKog https://t.co/IbB3xM75yw https://t.co/2XkuUPRx5v

  • Mashup Score: 16

    Coarctation of the aorta (CoA) accounts for approximately 5–8% of all congenital heart defects. Depending on the severity of the CoA and the presence of associated cardiac lesions, the clinical presentation and age vary. Developments in diagnosis and management have improved outcomes in this patient population. Even after timely repair, it is important to regularly screen for hypertension….

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    • RT @Sarah_Moharem: @NwchdN Comprehensive Review of Coarctation of the Aorta 🫀 https://t.co/usBU7amgpJ #ACHD #CHD @Sadaf_Raz @AchdExpert…