• Mashup Score: 3

    The prevalence of heart failure (HF) continues to rise steadily, and now more than 64 million people globally carry the diagnosis.1 Together with a 5-year survival rate of ∼ 50% and high rates of hospitalization, there are few other conditions across medicine that have such an unfortunate combination of being exceedingly common, morbid and deadly.2 Fortunately, for patients with HF with reduced…

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    • ⏱️to optimized 4 🏛️ GDMT The predominant determinant of clinical outcomes in HFrEF Urgency needed Don’t delay Start now Titrate now Time to Quadruple Guideline-Directed Medical Therapy as a Key Performance Measure for Heart Failure https://t.co/6tqH7Rehy6

  • Mashup Score: 3

    Randomized controlled trials (RCTs) are considered the gold standard for assessing the safety and efficacy of medical interventions. Inconsistencies between the prespecified protocol and trial publication can reduce the internal validity of trials. In this study, we sought to assess the prevalence and characteristics of heart failure RCTs that report outcomes different from those prespecified. Of…

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    • Can you guess the % of HF #RCTs in top journals that report #outcomes (including primary) inconsistently relative to analytic plans? Why does it matter? Check out this 📄 led by ⁦@TariqJamalSidd1⁩ ⁦@ShahzebKhanMD⁩ et al #TrialReporting #Bias https://t.co/1T87o6jrt1

  • Mashup Score: 1

    Randomized controlled trials (RCTs) are considered the gold standard for assessing the safety and efficacy of medical interventions. Inconsistencies between the prespecified protocol and trial publication can reduce the internal validity of trials. In this study, we sought to assess the prevalence and characteristics of heart failure RCTs that report outcomes different from those prespecified. Of…

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    • More than 1 in 10 trials reported outcomes inconsistent with those specified in trial registration websites, SAPs and protocols Inconsistent Outcome Reporting in Heart Failure Randomized Controlled Trials https://t.co/KNKcuROGTV

  • Mashup Score: 11

    Clinical rotations on the Heart Failure/LVAD/Heart Transplant services can be busy. They often demand our total immersion – managing complex hemodynamic perturbations, coordinating extracardiac care with consultants, getting to know the intricacies of patients’ personalities and support systems. Clinician fulfillment and heartache are often commingled in any given day with the rejoice of…

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    • As March comes to a close, #WeveBeenThinking about delivering #ConstructiveFeedback to trainees & colleagues @JCardFail… #FunctionNotFailure docs can lead… 👀 it out & let us know your thoughts 🙏🏽 What works? What doesn’t? @robmentz @CardioNerds @HFSA https://t.co/dGNIO2kzbX https://t.co/4kAj3w7N2T

  • Mashup Score: 22

    We assessed the prevalence of SCD in a Mediterranean HF cohort managed in a multidisciplinary HF clinic over 20 years and compared the observed proportion of SCD to the expected proportional occurrence based on the SPRM score.

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    • 🚨Editor's Pick from the March Issue of JCF🚨 "Sudden Cardiac Death in Heart Failure" Important article that gives a 20-Year Perspective From a Large Mediterranean Cohort By Codina, Bayes-Genis, et al Take Home Visual in 🧵 @dranulala @HFSA @JCardFail https://t.co/mpL1hKZfkV https://t.co/WJFwy82oxo