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Mashup Score: 5From bedside to recovery: exercise therapy for prevention of post-intensive care syndrome - Journal of Intensive Care - 24 day(s) ago
Background As advancements in critical care medicine continue to improve Intensive Care Unit (ICU) survival rates, clinical and research attention is urgently shifting toward improving the quality of survival. Post-Intensive Care Syndrome (PICS) is a complex constellation of physical, cognitive, and mental dysfunctions that severely impact patients’ lives after hospital discharge. This review provides a comprehensive and multi-dimensional summary of the current evidence and practice of exercise therapy (ET) during and after an ICU admission to prevent and manage the various domains of PICS. The review aims to elucidate the evidence of the mechanisms and effects of ET in ICU rehabilitation and highlight that suboptimal clinical and functional outcomes of ICU patients is a growing public health concern that needs to be urgently addressed. Main body This review commences with a brief overview of the current relationship between PICS and ET, describing the latest research on this topic. It
Source: jintensivecare.biomedcentral.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 4From bedside to recovery: exercise therapy for prevention of post-intensive care syndrome - Journal of Intensive Care - 1 month(s) ago
Background As advancements in critical care medicine continue to improve Intensive Care Unit (ICU) survival rates, clinical and research attention is urgently shifting toward improving the quality of survival. Post-Intensive Care Syndrome (PICS) is a complex constellation of physical, cognitive, and mental dysfunctions that severely impact patients’ lives after hospital discharge. This review provides a comprehensive and multi-dimensional summary of the current evidence and practice of exercise therapy (ET) during and after an ICU admission to prevent and manage the various domains of PICS. The review aims to elucidate the evidence of the mechanisms and effects of ET in ICU rehabilitation and highlight that suboptimal clinical and functional outcomes of ICU patients is a growing public health concern that needs to be urgently addressed. Main body This review commences with a brief overview of the current relationship between PICS and ET, describing the latest research on this topic. It
Source: jintensivecare.biomedcentral.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 65Role of the interstitium during septic shock: a key to the understanding of fluid dynamics? - Journal of Intensive Care - 4 month(s) ago
Background While not traditionally included in the conceptual understanding of circulation, the interstitium plays a critical role in maintaining fluid homeostasis. Fluid balance regulation is a critical aspect of septic shock, with a well-known association between fluid balance and outcome. The regulation of transcapillary flow is the first key to understand fluid homeostasis during sepsis. Main text Capillary permeability is increased during sepsis, and was classically considered to be necessary and sufficient to explain the increase of capillary filtration during inflammation. However, on the other side of the endothelial wall, the interstitium may play an even greater role to drive capillary leak. Indeed, the interstitial extracellular matrix forms a complex gel-like structure embedded in a collagen skeleton, and has the ability to directly attract intravascular fluid by decreasing its hydrostatic pressure. Thus, interstitium is not a mere passive reservoir, as was long thought, bu
Source: jintensivecare.biomedcentral.comCategories: General Medicine News, Hem/OncsTweet
A Review published in the Journal of Intensive Care summarizes the current evidence and practice of exercise therapy during and after an ICU admission to prevent and manage the various domains of post-intensive care syndrome. https://t.co/Dcz61Tr6VJ