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Mashup Score: 0
Benign histiocytic necrotizing lymphadenitis or Kikuchi-Fujimoto disease (KD) is a rare disease of unknown etiology. KD typically affects women less than 40 years of age and presents with persistent low-grade fever and enlargement of the cervical lymph nodes (LN).1 The presence of lymphadenopathy with systemic symptoms often raises concern for lymphoma, prompting LN biopsy. The LN…
Source: JAAD Case ReportsCategories: Dermatology, Latest HeadlinesTweet
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Mashup Score: 1Thoracic venous aneurysm underlying a lipoma - 2 year(s) ago
Venous aneurysmal dilatation is a rare pathology that has been reported few times in the literature. Compared to their arterial counterparts, venous aneurysms are much less prevalent and studied, and they lack well-delineated guidelines regarding their diagnosis and management. Most of clinical practice on the topic is dependent on the scarce evidence from case reports, case series, and…
Source: JAAD Case ReportsCategories: Dermatology, Latest HeadlinesTweet
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Mashup Score: 1Calcinosis cutis in the setting of severe COVID-19 infection - 2 year(s) ago
A growing body of data is unveiling the role of skin in understanding the pathophysiologic changes of COVID-19.1-3 Common cutaneous morphologies of COVID-19 include pernio-like lesions; eruptions that can be urticarial, macular, vesicular, or papulosquamous; and retiform purpura.1,3 Limited data exist on whether dystrophic calcification—the deposition of insoluble calcium salt in cutaneous and…
Source: JAAD Case ReportsCategories: Dermatology, Latest HeadlinesTweet
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Mashup Score: 0Granulomatous slack skin of the thigh developing since childhood - 2 year(s) ago
Granulomatous Slack Skin (GSS) is an exceedingly uncommon variant of mycosis fungoides (MF),1 that manifests as an indurated pendulous plaque commonly affecting the skin folds.2 The mean age of those afflicted is 37 years.2 Despite the challenge of determining the condition’s incidence rate owing to its rarity, GSS was estimated to constitute 1.2% of MF cases in the younger population.3 The…
Source: JAAD Case ReportsCategories: Dermatology, Latest HeadlinesTweet
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Mashup Score: 2
Delusional parasitosis (DP) is a psychiatric disorder characterized by a persistent yet false belief of being infested with parasites. Affected individuals often seek dermatologic or infectious disease care to identify the perceived organisms. Treatment has historically relied on antipsychotics given the delusional nature of the illness, but treatment studies are very limited and to date there…
Source: JAAD Case ReportsCategories: Dermatology, Latest HeadlinesTweet
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Mashup Score: 3
Dupilumab is a fully humanized monoclonal antibody to the interleukin 4 (IL-4) receptor alpha subunit, inhibiting IL-4 and IL-13 signaling pathways which leads to downregulation of T helper (Th) 2 mediated inflammation.1 There are several reports of drug hypersensitivity reactions (DHR) to dupilumab, including conjunctivitis, psoriasiform, eczematous, and lichenoid eruptions.2-4 It has been…
Source: JAAD Case ReportsCategories: Dermatology, Latest HeadlinesTweet
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Mashup Score: 0
Linear IgA bullous dermatosis (LABD) is a rare, autoimmune blistering skin disorder that involves the deposition of IgA at the dermoepidermal junction. This disease presents with widespread tense vesicles and bullae, clustered into rosettes. LABD can occur spontaneously or following drug exposure, and it can be seen in patients with underlying inflammatory bowel disease (IBD), most commonly…
Source: JAAD Case ReportsCategories: Dermatology, Latest HeadlinesTweet
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Mashup Score: 0
B-cell chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the United States.1 Patients are often asymptomatic but can present with leukemic infiltrates in the skin.2 Here we report the case of a patient diagnosed with CLL during Mohs micrographic surgery (MMS) after leukemic infiltrates were noted on Mohs frozen sections.
Source: JAAD Case ReportsCategories: Dermatology, Latest HeadlinesTweet
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Mashup Score: 1Dusky pink annular plaques with a vesicular border - 2 year(s) ago
A 27-year-old pregnant female at 22 weeks of gestation presented with an acute diffuse erythematous blistering rash on the upper and lower extremities bilaterally and abdomen for 1 week. The rash began around the umbilicus as itchy pink papules that evolved into painful dusky pink plaques with annular vesicles and bullae (Fig 1). Medical history was significant for prior preterm delivery via…
Source: JAAD Case ReportsCategories: Dermatology, Latest HeadlinesTweet
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Mashup Score: 1A rare presentation of secondary multiple miliary osteoma cutis - 2 year(s) ago
An 80-year-old male presented with firm pruritic skin-colored to yellow papules and nodules on his neck, chest, and back present for decades (Figs 1 and 2). In adolescence, he received radiation therapy for severe acne. Medications include emtricitabine and tenofovir alafenamide for HIV. As the appearance of the lesions preceded initiation of emtricitabine and tenofovir alafenamide by several…
Source: JAAD Case ReportsCategories: Dermatology, Latest HeadlinesTweet
A woman in her 20s presented to the dermatology clinic with a complaint of a #pruriticrash on her left ear. Complete review of systems was otherwise negative. Medical history was significant for biopsy-confirmed KD diagnosed at an outside hospital in 2015. https://t.co/7lgC0OeW9s