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Mashup Score: 83Machine Learning Deserves Better Than This - 3 year(s) ago
This is an excellent overview at Stat on the current problems with machine learning in healthcare. It’s a very hot topic indeed, and has been for some time. There has especially been a flood of manuscripts during the pandemic, applying ML/AI techniques to all sorts of coronavirus-related issues. Som
Source: In the PipelineCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 15A Word on Blog Topics - 3 year(s) ago
I’ve had some queries that make me think that a brief meta-blog entry might be in order. I’m still fielding a lot of coronavirus queries, not all of which by any means make it up here to the blog. And at the same time, I’m also getting a lot of suggestions that are more in the classic mode: interest
Source: In the PipelineCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 3Waiving IP - 3 year(s) ago
The announcement by the Biden administration about waiving IP rights to the coronavirus vaccines obviously calls for some comment. Keep in mind that I have been doing research in the pharma industry for over 30 years now, so my viewpoint is obviously going to be affected by that, for better and for
Source: In the PipelineCategories: HIV/AIDS, Latest HeadlinesTweet
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Mashup Score: 9CRISPR Editing in Primates - 3 year(s) ago
There’s some really interesting CRISPR news out today, and it’s likely to be a forerunner of much more news to come. A research team has demonstrated what looks like robust, long-lasting effects in a primate model after one injection of the CRISPR enzymatic machinery. There have been plenty of roden
Source: In the PipelineCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 1Coronavirus Origins - 3 year(s) ago
I’m going to regret writing about this, but it’s not a topic to be ignored. Where did the current coronavirus come from? If you ask that question, you get all sorts of answers from all sorts of people. Let me downgrade some of those right up front. To start at the far end of the fever scale, I do
Source: In the PipelineCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 2Curcumin Will Waste Your Time - 3 year(s) ago
I really enjoyed reading this article in J. Med. Chem. on curcumin. (Update: here’s the take over at Practical Fragments). That’s a well-known natural product, found in large quantities in turmeric root (which is where most of the yellow color comes from). It has, over the years, been a hit in many,
Source: In the PipelineCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 1Tie Me Proteins All Down, Sport - 3 year(s) ago
There are a lot of slick ideas in molecular and chemical biology that depend on immobilizing proteins or small molecules onto solid supports. Consider affinity chromatography: if you can tether a “bait” onto some solid matrix, you can then flow all sorts of mixtures over it (gorp from freshly lysed
Source: In the PipelineCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 46Brazil Rejects the Gamaleya Vaccine - 3 year(s) ago
We have two pieces of news about the Gamaleya Institute’s “Sputnik-V” vaccine today. Neither of them are going to be enjoyable to go into. First off, many may have heard that the Brazilian regulatory authorities had a hearing yesterday to see if this vaccine would be approved for use there. They
Source: In the PipelineCategories: Healthcare Professionals, Latest HeadlinesTweet-
“Step up and act like responsible drug developers.” A great take on Sputnik from @Dereklowe. https://t.co/kAI43NYsxW
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.@Dereklowe on the Brazilian regulatory agency's decision to refuse to authorize Sputnik V for use there. The country needs vaccine. That it won't green light this one is noteworthy. https://t.co/sXtGSpPXWH
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Mashup Score: 7Great Malaria Vaccine News - 3 year(s) ago
Excellent news today: we have word of the most effective malaria vaccine yet discovered. A year-long trial in Burkina Faso has shown 77% efficacy, which is by far the record, and which opens the way to potentially relieving a nearly incalculable burden of disease and human suffering. This is a co
Source: In the PipelineCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 3Vaccine Side Effects Q and A - 3 year(s) ago
So what’s the side effect that caused the J&J vaccine pause? Blood clotting – but not the usual kind. This appears to be the same (or very similar) to the problem seem with the Oxford/AstraZeneca vaccine in Europe, and both are very similar to a known syndrome called heparin-induced thrombocy
Source: In the PipelineCategories: Infectious Disease, Latest HeadlinesTweet
Machine learning papers based on COVID-19 lung scans are, almost without exception, worthless. Why is work of this low quality still getting constantly published, asks @Dereklowe https://t.co/NjsEFrsmik https://t.co/NjsEFrsmik