• Mashup Score: 1

    The fight against neurodegenerative diseases is one of the key direction of modern medicine. Unfortunately, the difficulties in understanding the factors underlying the development of neurodegeneration hinder the development of breakthrough therapeutics that can stop or at least greatly slow down the progression of these diseases. In this review, it is considered the disruption of…

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    • RT @Rothstein_Lab: The Role of Impaired Mitochondrial Transport in the Development of Neurodegenerative Diseases https://t.co/pgVh0kS0Y4

  • Mashup Score: 5

    Cardiac Rehabilitation programs have shown to improve outcomes. The COVID-19 pandemic has posed barriers to these programs. A virtual platform might be a good solution to these challenges. Tele Cardiac Rehabilitation and remote patient monitoring provide an excellent alternative practical solution.

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    • @GiuseppeGalati_ @American_Heart @ACCinTouch @JACCJournals @gcfmd @JavedButler1 @JJheart_doc @DrMarthaGulati @gbiondizoccai @purviparwani @FrancescoPaneni @AnastasiaSMihai @mmamas1973 @ShelleyZieroth @RFE_Pedretti @KTamirisaMD @DrRajivsankar Excellent!! Cardiac rehab is underutilized by most who have an indication for it- virtual CR could help https://t.co/64LSoF0LXS https://t.co/i3aKJmRmxf

  • Mashup Score: 6

    Background: Recently, questions around the efficacy and effectiveness of Fractional Flow Reserve (FFR) have arisen in various clinical settings. Methods: The Clinical Outcome of FFR-guided Revascularization Strategy of Coronary Lesions (HALE-BOPP) study is an investigator-initiated, multicentre, international prospective study enrolling patients who underwent FFR measurement on at…

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    • RT @Tebaldi_Matteo: HALE-BOPP https://t.co/4CLcmXWW8m 📌1305 👤 (2422 vessels) 📌50% ACS- 3.6 yrs median FUP 📌FFR-deferred vessels: TVF 0.024%…

  • Mashup Score: 7

    Therapeutic approaches based on gene silencing technologies represent a new opportunity to manage hypercholesterolemia. Inclisiran is a small interfering RNA that targets proprotein convertase subtilisin/kexin type 9 (PCSK9) mRNA. Clinical studies have demonstrated that inclisiran is effective, safe, and well-tolerated in reducing low-density lipoprotein cholesterol (LDL-C) in…

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    • Published our review article "Inclisiran: A New Pharmacological Approach for Hypercholesterolemia". Thank you @doctstefania for leading our working group in the production of this paper! https://t.co/OXHO3bOhec #cardiotwitter #cvprev https://t.co/WTX8R3wpXJ

  • Mashup Score: 0

    Coronary stent fracture (SF) is a potential cause of stent failure increasing the risk for in-stent restenosis, stent thrombosis, target lesion revascularization and major adverse cardiac events. Overall incidence of SF ranges from <1.0% up to 18.6% and SF can be found in up to 60% of failed devices. Advanced imaging techniques have improved the detection of SF. However, defining...

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    • Coronary stent fracture: Is it common? Which are its risk factors? How should it be managed? Here's a recent review on the topic! https://t.co/8agGqW8lxv https://t.co/KToHo86jPl

  • Mashup Score: 50

    Background: The term myocardial infarction with non-obstructive coronary arteries (MINOCA), defines a puzzling event occurring in the absence of obstructive coronary artery disease on coronary angiography and without an overt potential cause. However, a practical diagnostic work-up is often difficult, due to the heterogeneous etiologies and pathophysiology of MINOCA. This review…

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    • RT @OrlandoRPN: Infarto al Miocardio sin Obstrucción Coronaria #MINOCA🫀 Excelente revisión: https://t.co/ZlpmNxPgzM https://t.co/GjJeUZ8sxf

  • Mashup Score: 45

    Percutaneous coronary intervention (PCI) is considered a relatively safe procedure associated with low rates of complications, but is inevitably associated with short and mid-to-long term increased bleeding risk. Besides the short term risk associated with the arterial access to perform PCI, enhanced bleeding risk persists for several months, given the need for antithrombotic…

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    • RT @MattiaGalli10: How to prevent bleeding in patients undergoing PCI? https://t.co/B5ee69ZxUe https://t.co/efFgZ9I5LO

  • Mashup Score: 7

    Following percutaneous coronary intervention (PCI), an initial course of dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 inhibitor (P2Y12-i) is recommended to minimize the risk of thrombotic complications. After the initial period of DAPT, antiplatelet monotherapy, usually consisting of aspirin, is administered for long-term secondary prevention. However, over the last…

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    • RT @AGrecoMD: P2Y12 receptor inhibitor monotherapy for secondary prevention after PCI: an updated review article. https://t.co/ennwOLVyVm @…

  • Mashup Score: 1

    In patients with cancer, myocardial infarction (MI) has distinct features and mechanisms compared to the non-oncology population. Triggers of myocardial ischemia specific to the oncology population have been increasingly identified. Coronary plaque disruption, coronary vasospasm, coronary microvascular dysfunction, spontaneous coronary artery dissection, and coronary oxygen…

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    • Is MINOCA/INOCA a potential cardiotoxic sequelae of cancer biology and/or its treatments? @dinubalanescu @TDonisan et al explore this poorly understood disease process within the #cardioonc realm in this review--much more study is needed! https://t.co/kqlg7QV1oE https://t.co/1NWM3HEa0E