• Mashup Score: 11
    Science Immunology - 3 year(s) ago

    August 2021 Vol 6, Issue 62Research ArticlesEditors’ Choice About The Cover ONLINE COVER Carnivoran Caspase Evolution. This month’s cover shows two cheetahs scanning the surrounding grasslands in Liuwa Plain National Park in Zambia. Devant et al. characterized the functional activity of cloned caspase-1/4 hybrid…

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    • The new August issue of Science #Immunology is out! Check out new research on differences of the caspase enzyme among dogs, cats, and humans, and how virtual memory T cells act as a bridge between innate and adaptive #immune systems: https://t.co/686yNTLxqG https://t.co/xXdhAfhTZB

  • Mashup Score: 53
    Science Immunology - 3 year(s) ago

    Resident Kupffer cells and neutrophils drive liver toxicity in cancer immunotherapy By Marie Siwicki, Nicolas A. Gort-Freitas, Marius Messemaker, Ruben Bill, Jeremy Gungabeesoon, Camilla Engblom, Rapolas Zilionis, Christopher Garris, Genevieve M. Gerhard, Anna Kohl, Yunkang Lin, Angela E. Zou, Chiara Cianciaruso, Evangelia Bolli, Christina Pfirschke, Yi-Jang Lin, Cecile Piot, John E….

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    • The July 2021 issue of Science #Immunology is out! Read about offsetting the adverse effects of checkpoint blockade #cancer #immunotherapy and the role of #epigenetics in autoimmune disease. More to come, as July continues: https://t.co/686yNU38ie https://t.co/Pumm7J7Tio

  • Mashup Score: 37
    Science Immunology - 3 year(s) ago

    June 2021 Vol 6, Issue 60FocusResearch Articles Intestinal cDC1 drive cross-tolerance to epithelial-derived antigen via induction of FoxP3+CD8+ Tregs By Thorsten Joeris, Cristina Gomez-Casado, Petra Holmkvist, Simon J. Tavernier, Aaron Silva-Sanchez, Luisa Klotz, Troy D. Randall, Allan M. Mowat, Knut Kotarsky,…

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    • The new June issue of #Science #Immunology is out! Read about the cellular players that control T cell tolerance outside of the thymus, the factors that help confine B cells to their germinal centers, and more to come... https://t.co/686yNTLxqG https://t.co/5bQhqvaW1S

  • Mashup Score: 60
    Science Immunology - 3 year(s) ago

    ONLINE COVER Stromal Cell Specialization. This month’s cover shows dual in situ hybridization detection of mRNA for R-spondin 3 (Rspo3) and the alpha chain of the platelet-derived growth factor receptor (Pdgfra) in mouse colon sections on day 11 after infection with Citrobacter rodentium. Pdgfra (red) is expressed in subepithelial fibroblasts while Rspo3 (blue) is selectively expressed in a…

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    • The new May cover of #Science #Immunology is out! In this issue, read about gut repair programs and how inflammasomes may promote the success of radiation therapy for #cancer. More to come here ...https://t.co/686yNTLxqG https://t.co/h70LZ3nkYW

  • Mashup Score: 4
    Science Immunology - 3 year(s) ago

    ONLINE COVER Splenic DCs Sticking to the DC-SCRIPT. This month’s cover captures the expression of the transcriptional regulator DC-SCRIPT in the mouse spleen using a dtTomato reporter allele. This confocal microscopy image highlights DC-SCRIPT expression in dendritic cells (DCs, red) that are embedded in the T cell zone (CD3, blue), surrounded by B cells (IgM, green) and the marginal zone (CD169,…

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    • The new April issue of #Science #Immunology is out! This week, learn all about dendritic cells (in red, below), as two separate studies clarify what regulates their differentiation and how they recognize viruses. More to come: https://t.co/686yNTLxqG https://t.co/N7CxsHkCjR

  • Mashup Score: 5

    Read the Latest Issue of Science 12 March 2021 Vol 371, Issue 6534 Table of Contents Feature A call to arms COVID-19: Economics Market design to accelerate COVID-19 vaccine supply Film Pandora’s pandemic SCI COMMUN News at a glance Climate Change Who is stirring the waters? Working Life A mother’s plea …

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    • Fishing out microbes from a relatively unexplored central Pacific zone in #Kiribati, @BostonChildrens, @harvardmed scientists have identified several new species of #bacteria that seem to violate one of the fundamental tenets of #immunology: https://t.co/DcxnCNhraN https://t.co/CKX0ky8anV

  • Mashup Score: 9
    Science Immunology - 3 year(s) ago

    SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8+ T cell responses By , Maximilian Koblischke, Venugopal Gudipati, Luis Fernando Montaño-Gutierrez, Mark Smyth, Alexandra Popa, Jakob-Wendelin Genger, Lukas Endler, David M. Florian, Vanessa Mühlgrabner, Marianne Graninger, Stephan W. Aberle, Anna-Maria Husa, Lisa Ellen Shaw, Alexander Lercher, Pia Gattinger,…

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    • The new March cover of Science #Immunology is out! In this issue, learn about an #immune system and nervous system crossover that's critical for controlling parasitic infection, and more to come...https://t.co/686yNTLxqG https://t.co/QpnLgcta7s

  • Mashup Score: 3
    Science Immunology - 3 year(s) ago

    February 2021 Vol 6, Issue 56FocusResearch Articles E-cadherin is regulated by GATA-2 and marks the early commitment of mouse hematopoietic progenitors to the basophil and mast cell fates By Anaïs Wanet, Mahmoud A. Bassal, Sweta B. Patel, Francisco Marchi, Samanta A. Mariani, Nouraiz Ahmed, Haoran Zhang, Marta Borchiellini, Sisi Chen, Junyan Zhang,…

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    • The new February issue of Science #Immunology out! In this issue, scientists pinpoint drivers of #multiplesclerosis in the gut, elucidate the origins of basophils and mast cells, and more to come...https://t.co/686yNTLxqG https://t.co/hA2H29mnmz

  • Mashup Score: 2
    Science Immunology - 3 year(s) ago

    December 2020 Vol 5, Issue 54FocusResearch ArticlesEditors’ Choice About The Cover ONLINE COVER Coral Calamity. This month’s cover is an underwater photograph showing a bleached stony coral (genus Pocillopora) on a reef near American Samoa. Bleaching occurs…

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    • The new December issue of Science #Immunology is out! Read about a critical regulator of innate lymphoid cell differentiation, #coral reef destruction that may involve the same cell death pathways as vertebrates, and more to come! https://t.co/686yNTLxqG #marineecology https://t.co/b0SCVtFB85

  • Mashup Score: 6
    Science Immunology - 4 year(s) ago

    ONLINE COVER Pneumonia Prophylaxis. This month’s cover depicts intramuscular administration of a vaccine to an elderly man. Lower respiratory virus infections, including influenza and SARS-CoV-2, are more likely to progress to severe pneumonia and a fatal outcome in senior citizens. There is an urgent need for vaccines that show comparable efficacy in seniors and younger individuals. Using a…

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    • Check out the new November cover of Science #Immunology! In this issue: an age-associated paradox found in older mice following influenza-driven #pneumonia; a review of a “master regulator” of T cell development and response, and more to come: https://t.co/686yNTLxqG https://t.co/sTJ13yJrHW