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Mashup Score: 5Myeloma — HaemBase - 1 year(s) ago
Cytogenetics NotesThe poor risk of t(14;16) may be partly overcome by use of bortezomib-based therapyThe risk of t(11;14) may be higher than previously thought, but may also be a biomarker for predicting response to venetoclax (BCL2 inhibitor)Prognosis gets poorer with increasing copy numbers of 1qIf patients achieve MRD-negativity (by flow) —> 3-yr PFS similar regardless of cytogenetic risk…
Source: HaemBaseCategories: Latest Headlines, Partners & KOLsTweet
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Mashup Score: 4MHV in Pregnancy — HaemBase - 2 year(s) ago
Intro Estimated incidence of MHV in pregnancy = 3.7 per 100,000 pregnanciesHigh maternal risks associated with MHV in pregnancy9% maternal mortality41% severe morbidity16% valve thrombosis9% StrokeHigh foetal risks associated with MHV in pregnancyMiscarriage, stillbirth, foetal haemorrhage, warfarin-induced teratogenicityAbove data from UK Obstetric Surveillance SystemEstimate only 28% of…
Source: HaemBaseCategories: Hem/Oncs, Latest HeadlinesTweet-
RT @TomboxaneA2: Haembase update: notes on the new BSH guideline on mechanical heart valves in pregnancy. https://t.co/UjpeaaaVVK https:/…
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Mashup Score: 1Atypical CML — HaemBase - 3 year(s) ago
DefinitionAtypical Chronic Myeloid Leukaemia, BCR-ABL1 negative is a MDS/MPN overlap disorder (e.g. like CMML)Presents with a dysplastic neutrophil leukocytosis, often with additional multi-lineage dysplasiaBCR-ABL1, PDGFRA and PDGFRB mutations are not presentEpidemiologyRare disorder, typically of older ageMedian age at diagnosis: 60-70PresentationSymptomatic…
Source: HaemBaseCategories: Hem/Oncs, Latest HeadlinesTweet-
RT @TomboxaneA2: Thank you for reading (and voting) aCML - https://t.co/6FVx203YyL MDS - https://t.co/zJybzcU7PC More photos - https://t.c…
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Mashup Score: 11Classical Hodgkin — HaemBase - 3 year(s) ago
CD30+, CD15+CD45-, CD20-, CD3-epidemiologyAnnual Incidence 2.7 / 100,000 in UKTwo peaks at 20-34 and >70Initial Work-upBloods – FBC, ESR, U&E, LFT, Bone profile, HIV, hep B/CBiopsy – 4 histological subtypes – Nodular sclerosis, mixed cellularity, lymphocyte-rich and lymphocyte-depleted – but no difference in outcomesPET-CT – For staging. Detects bone involvement. BM biopsy not required.Fertility…
Source: HaemBaseCategories: Hem/Oncs, Latest HeadlinesTweet-
RT @TomboxaneA2: Haembase updated with the new BSH guidelines on 1st line treatment of Hodgkin. Haembase - https://t.co/D41gruRymT BSH -…
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Mashup Score: 8Classical Hodgkin — HaemBase - 3 year(s) ago
CD30+, CD15+CD45-, CD20-, CD3-epidemiologyAnnual Incidence 2.7 / 100,000 in UKTwo peaks at 20-34 and >70Initial Work-upBloods – FBC, ESR, U&E, LFT, Bone profile, HIV, hep B/CBiopsy – 4 histological subtypes – Nodular sclerosis, mixed cellularity, lymphocyte-rich and lymphocyte-depleted – but no difference in outcomesPET-CT – For staging. Detects bone involvement. BM biopsy not required.Fertility…
Source: HaemBaseCategories: Hem/Oncs, Latest HeadlinesTweet-
RT @TomboxaneA2: Haembase updated with the new BSH guidelines on 1st line treatment of Hodgkin. Haembase - https://t.co/D41gruRymT BSH -…
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Mashup Score: 10Peripheral Blood — HaemBase - 4 year(s) ago
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 …
Source: HaemBaseCategories: Hem/Oncs, Latest HeadlinesTweet-
RT @TomboxaneA2: Some new photos added to the Haembase image library today - https://t.co/JL28tIaj87 https://t.co/CkgYlU6SRg
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RT @TomboxaneA2: Haembase Update: UK options for relapsed myeloma updated after the latest NICE changes. https://t.co/L6ffod1y9e What have…