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Mashup Score: 2The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits - 1 year(s) ago
The Type 2 Diabetes Knowledge Portal (T2DKP) is an innovative resource that democratizes access to human genetic and genomic data. In this issue, Costanzo et al. describe how both novice and expert users can use the T2DKP in their research.
Source: Cell MetabolismCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Habitual daily intake of a sweet and fatty snack modulates reward processing in humans - 1 year(s) ago
Edwin Thanarajah et al. show that daily snacking on an unhealthy food reduces preference for low-fat food and rewires brain reward circuits to enhance response to a palatable food and upregulate neural computations supporting learning beyond ingestive behavior. Effects are observed despite no change in body weight or metabolic health.
Source: Cell MetabolismCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 2Gut-microbiome-expressed 3β-hydroxysteroid dehydrogenase degrades estradiol and is linked to depression in premenopausal females - 1 year(s) ago
Our research demonstrates that the degradation of estradiol by gut microbes containing 3β-HSD leads to a decrease in serum estradiol levels, causing depression in female mice. Our study reveals both a novel mechanism for depression in females linked to gut microbes and possible intervention targets.
Source: Cell MetabolismCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 16Gut-microbiome-expressed 3β-hydroxysteroid dehydrogenase degrades estradiol and is linked to depression in premenopausal females - 1 year(s) ago
Our research demonstrates that the degradation of estradiol by gut microbes containing 3β-HSD leads to a decrease in serum estradiol levels, causing depression in female mice. Our study reveals both a novel mechanism for depression in females linked to gut microbes and possible intervention targets.
Source: Cell MetabolismCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 18Rejuvenating muscle stem cells with the glutathione system - 1 year(s) ago
Aging results from the combination of complex processes still largely undefined. In this issue, Benjamin et al. use multiomic analysis to reveal a causative role of altered glutathione (GSH) synthesis and metabolism in age-dependent muscle stem cell (MuSC) dysfunction, casting light on novel mechanisms regulating stem cell function and on therapeutic approaches to improve defective regeneration…
Source: Cell MetabolismCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 5The global burden of metabolic disease: Data from 2000 to 2019 - 1 year(s) ago
Global estimates from the GBD Study 2019 reveal decreasing mortality rates between 2000 and 2019 for hyperlipidemia, hypertension, and NAFLD, but not for T2DM and obesity. The highest mortality rate due to metabolic disease was found in the Eastern Mediterranean, and in low- to low-middle-income countries. Urgent attention is needed to address high and unchanging mortality rates as well as…
Source: Cell MetabolismCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0The global burden of metabolic disease: Data from 2000 to 2019 - 1 year(s) ago
Global estimates from the GBD Study 2019 reveal decreasing mortality rates between 2000 and 2019 for hyperlipidemia, hypertension, and NAFLD, but not for T2DM and obesity. The highest mortality rate due to metabolic disease was found in the Eastern Mediterranean, and in low- to low-middle-income countries. Urgent attention is needed to address high and unchanging mortality rates as well as…
Source: Cell MetabolismCategories: Hematologists1, Latest HeadlinesTweet
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Mashup Score: 3The global burden of metabolic disease: Data from 2000 to 2019 - 1 year(s) ago
Global estimates from the GBD Study 2019 reveal decreasing mortality rates between 2000 and 2019 for hyperlipidemia, hypertension, and NAFLD, but not for T2DM and obesity. The highest mortality rate due to metabolic disease was found in the Eastern Mediterranean, and in low- to low-middle-income countries. Urgent attention is needed to address high and unchanging mortality rates as well as…
Source: Cell MetabolismCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 1Complementary lateral hypothalamic populations resist hunger pressure to balance nutritional and social needs - 1 year(s) ago
Animals continuously weigh hunger and thirst against competing needs, such as social contact and mating, according to state and opportunity. Here, Petzold et al. show that leptin receptor-expressing and neurotensin-expressing neurons in the lateral hypothalamus resist immediate nutritional needs and flexibly prioritize competing needs despite hunger or thirst.
Source: Cell MetabolismCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0Complementary lateral hypothalamic populations resist hunger pressure to balance nutritional and social needs - 1 year(s) ago
Animals continuously weigh hunger and thirst against competing needs, such as social contact and mating, according to state and opportunity. Here, Petzold et al. show that leptin receptor-expressing and neurotensin-expressing neurons in the lateral hypothalamus resist immediate nutritional needs and flexibly prioritize competing needs despite hunger or thirst.
Source: Cell MetabolismCategories: General Medicine News, Latest HeadlinesTweet
The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits https://t.co/s3yJb8HkCW https://t.co/qR3vrCklpV