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Mashup Score: 2Risk of venous thromboembolism in patients with rheumatoid arthritis: a meta-analysis of observational studies - BMC Rheumatology - 3 month(s) ago
Background Thrombotic events, such as venous thromboembolism (VTE) are a major health complication linked to rheumatoid arthritis (RA). We performed a meta-analysis to evaluate the risk of VTE, including deep vein thrombosis (DVT) and pulmonary embolism (PE), in adults with RA compared to the general population. Methods MEDLINE and EMBASE databases were searched from inception to April 2022 to identify publications meeting the following criteria: (1) prospective and retrospective original data from cohort or case-control studies; (2) pre-specified RA definition; (3) clearly defined VTE outcomes; (4) reported risk estimate and 95% confidence intervals (95% CIs); (5) at least sex- and age-matched to comparison group; and (6) English language. Of 372 studies screened, 14 were included (602,760 RA patients, 123,076 VTE events) and their quality was assessed by an adaptation of the STROBE quality scoring scale. Results The pooled risk ratios of VTE, DVT and PE in patients with RA were 1.57
Source: bmcrheumatol.biomedcentral.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 5Risk of venous thromboembolism in patients with rheumatoid arthritis: a meta-analysis of observational studies - BMC Rheumatology - 3 month(s) ago
Background Thrombotic events, such as venous thromboembolism (VTE) are a major health complication linked to rheumatoid arthritis (RA). We performed a meta-analysis to evaluate the risk of VTE, including deep vein thrombosis (DVT) and pulmonary embolism (PE), in adults with RA compared to the general population. Methods MEDLINE and EMBASE databases were searched from inception to April 2022 to identify publications meeting the following criteria: (1) prospective and retrospective original data from cohort or case-control studies; (2) pre-specified RA definition; (3) clearly defined VTE outcomes; (4) reported risk estimate and 95% confidence intervals (95% CIs); (5) at least sex- and age-matched to comparison group; and (6) English language. Of 372 studies screened, 14 were included (602,760 RA patients, 123,076 VTE events) and their quality was assessed by an adaptation of the STROBE quality scoring scale. Results The pooled risk ratios of VTE, DVT and PE in patients with RA were 1.57
Source: bmcrheumatol.biomedcentral.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 1Risk of venous thromboembolism in patients with rheumatoid arthritis: a meta-analysis of observational studies - BMC Rheumatology - 3 month(s) ago
Background Thrombotic events, such as venous thromboembolism (VTE) are a major health complication linked to rheumatoid arthritis (RA). We performed a meta-analysis to evaluate the risk of VTE, including deep vein thrombosis (DVT) and pulmonary embolism (PE), in adults with RA compared to the general population. Methods MEDLINE and EMBASE databases were searched from inception to April 2022 to identify publications meeting the following criteria: (1) prospective and retrospective original data from cohort or case-control studies; (2) pre-specified RA definition; (3) clearly defined VTE outcomes; (4) reported risk estimate and 95% confidence intervals (95% CIs); (5) at least sex- and age-matched to comparison group; and (6) English language. Of 372 studies screened, 14 were included (602,760 RA patients, 123,076 VTE events) and their quality was assessed by an adaptation of the STROBE quality scoring scale. Results The pooled risk ratios of VTE, DVT and PE in patients with RA were 1.57
Source: bmcrheumatol.biomedcentral.comCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 2
Background To investigate whether baseline serum cartilage oligomeric matrix protein (COMP), patient characteristics, traditional cardiovascular disease (CVD) risk factors and disease activity over time predict CVD, in early rheumatoid arthritis (RA). Methods This study included patients with early RA (
Source: bmcrheumatol.biomedcentral.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 6
Background The effects and their magnitudes of sex on disease activity indices for rheumatoid arthritis are not clear. We aimed to comprehensively evaluate the influence of sex on disease activity indices in the real-world setting using a large observational database. Methods We analyzed 14,958 patients registered in the National Database of Rheumatic Diseases in Japan (NinJa) in 2017. We evaluated the sex differences in the 28-joint disease activity score (DAS28) using erythrocyte sedimentation rate (ESR), DAS28 using C-reactive protein (DAS28-CRP), Simplified Disease Activity Index (SDAI), and Clinical Disease Activity Index by disease activity category using Cliff’s delta and regression analysis. Differences in the share of components of indices were evaluated using permutational multivariate analysis of variance. Correction equations were constructed to estimate the number of misclassification in male patients who achieve DAS28-ESR remission. Results DAS28-ESR showed higher values
Source: bmcrheumatol.biomedcentral.comCategories: General Medicine News, General HCPsTweet
A meta-analysis published in #BMCRheumatol finds that patients with rheumatoid arthritis are at a higher risk of venous thromboembolism, deep vein thrombosis and pulmonary embolism. https://t.co/ehp8F35CcO