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Mashup Score: 1Serum miRNA125a-5p, miR-125b-5p, and miR-433-5p as biomarkers to differentiate between posterior circulation stroke and peripheral vertigo - 4 year(s) ago
Acute vertigo is a common presentation of inner ear disease. However, it can also be caused by more serious conditions, especially posterior circulation stroke. Differentiating between these two conditions by clinical presentations and imaging studies during the acute phase can be challenging. This study aimed to identify serum microRNA (miRNA) candidates that could differentiate between…
Source: BMC NeurologyCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 0
The ventricular system plays a vital role in blood-cerebrospinal fluid (CSF) exchange and interstitial fluid-CSF drainage pathways. CSF is formed in the specialized secretory tissue called the choroid plexus, which consists of epithelial cells, fenestrated capillaries and the highly vascularized stroma. Very little is currently known about the role played by the ventricles and the choroid plexus…
Source: BMC NeurologyCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 1Increased serum IL-36γ levels are associated with disease severity in myasthenia gravis patients - 4 year(s) ago
Interleukin 36 (IL-36), as a gradually recognized cytokine, is involved in the occurrence and evolution of autoimmune diseases. Nevertheless, the relationship between myasthenia gravis (MG) and IL-36 is rarely reported. We evaluated the serum levels of IL-36 (IL-36α, IL-36β and IL-36γ) by enzyme-linked immunosorbent assay (ELISA). Further, clinical parameters in 97 MG patients and 49 healthy…
Source: BMC NeurologyCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 1LSVT-BIG therapy in Parkinson’s disease: physiological evidence for proprioceptive recalibration - 4 year(s) ago
There is growing evidence for proprioceptive dysfunction in patients with Parkinson’s disease (PD). The Lee Silvermann Voice Treatment-BIG therapy (LSVT-BIG), a special training program aiming at an increase of movement amplitudes in persons with PD (PwPD), has shown to be effective on motor symptoms. LSVT-BIG is conceptionally based on improving bradykinesia, in particular the decrement of…
Source: BMC NeurologyCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 3Different predictors after stroke depending on functional dependency at discharge: a 5-year follow up study - 4 year(s) ago
Level of dependency after a stroke is important for long-term outcome in several aspects, but less is known about important predictors for outcome depending on functional dependency. The aim of the current study was to investigate self-perceived outcome and identify possible predictors of strength, participation, and emotional outcome 5 years after stroke based on functional dependency at…
Source: BMC NeurologyCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 4Acute encephalopathy with elevated CSF inflammatory markers as the initial presentation of COVID-19 - 4 year(s) ago
COVID-19 is caused by the severe acute respiratory syndrome virus SARS-CoV-2. It is widely recognized as a respiratory pathogen, but neurologic complications can be the presenting manifestation in a subset of infected patients. We describe a 78-year old immunocompromised woman who presented with altered mental status after witnessed seizure-like activity at home. She was found to have SARS-CoV-2…
Source: BMC NeurologyCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 1Clinical features of Guillain–Barré syndrome patients with elevated serum creatine kinase levels - 4 year(s) ago
It is not well defined whether Guillain–Barré syndrome (GBS) patients with elevated serum creatine kinase (CK) levels have characteristic clinical features and are related to the subgroups of GBS. We retrospectively studied 51 consecutive patients with GBS, who visited our hospital, and compared clinical, laboratory and electrophysiological findings between patients with and without elevated CK…
Source: BMC NeurologyCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 3A self-administered, artificial intelligence (AI) platform for cognitive assessment in multiple sclerosis (MS) - 4 year(s) ago
Cognitive impairment is common in patients with multiple sclerosis (MS). Accurate and repeatable measures of cognition have the potential to be used as markers of disease activity. We developed a 5-min computerized test to measure cognitive dysfunction in patients with MS. The proposed test – named the Integrated Cognitive Assessment (ICA) – is self-administered and language-independent….
Source: BMC NeurologyCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 1
Mild cognitive impairment (MCI) is an intermediate stage between normal aging and dementia. Studies on MCI progression are important for Alzheimer’s disease (AD) prevention. 18F fluoro-deoxy-glucose positron emission tomography (FDG-PET) has been proven to be a powerful tool for measuring cerebral glucose metabolism. In this study, we proposed a classification framework for MCI prediction with…
Source: BMC NeurologyCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 3Functional brain network mechanism of executive control dysfunction in temporal lobe epilepsy - 4 year(s) ago
Executive control dysfunction is observed in a sizable number of patients with temporal lobe epilepsy (TLE). Neural oscillations in the theta band are increasingly recognized as having a crucial role in executive control network. The purpose of this study was to investigate the alterations in the theta band in executive control network and explore the functional brain network mechanisms of…
Source: BMC NeurologyCategories: NeurologyTweet
Serum miRNA125a-5p, miR-125b-5p, and miR-433-5p as biomarkers to differentiate between posterior circulation stroke and peripheral vertigo https://t.co/gY6fQQ32P6