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Mashup Score: 7Mind the (preterm) gap: inequality in the UK’s current RSV immunisation approach will leave many preterm babies unprotected against RSV this winter - 2 month(s) ago
The UK Health Security Agency (UKHSA) recently announced respiratory syncytial virus (RSV) vaccination programmes to protect babies by vaccinating pregnant women at 28 weeks’ gestation, and older adults aged 75 and over.1 The decision, which offers infants protection from RSV for at least 6 months, is extremely welcome, supported by the Joint Committee on Vaccination and Immunisation (JCVI) recommendation in June 2023 (updated September 2023),2 and an open letter from the Royal College of Paediatrics and Child Health(RCPCH) in March 2024 urging policy implementation. The JCVI recommendation reviewed two products; first, infant immunisation through a single dose of anti-F protein extended half-life monoclonal antibody (nirsevimab, developed by Sanofi and AstraZeneca, marketed as Beyfortus), and second, maternal vaccination with a bivalent pre-fusion F protein (marketed as Abrysvo, manufactured by Pfizer). Both products were found to offer favourable RSV prophylaxis, leading to the Depar
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Mashup Score: 12
In contrast to the editorial, Defining Surgical Success, 1 we advocate for including the voices of patients and parents when defining how successfully children with surgical conditions have been treated. The editorial proposes, without supporting evidence, definitions of successful treatment of key conditions. For children with oesophageal atresia, the definition proposed is the child leaves hospital neurologically intact and feeding orally following one thoracotomy . This definition ignores the fact that parents and patients have highlighted how problems caused by oesophageal atresia often continue throughout life.2 The definition proposed for Hirschsprung’s disease, a child leaving hospital defecating through their anus after one laparoscopic procedure , is similarly problematic. Currently, 60% of children with Hirschsprung’s disease are incontinent of faeces at primary school.3 Many of these children will have left hospital …
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Mashup Score: 1
Objective To describe the association of respiratory viral test results and the risk of invasive bacterial infection (IBI) for febrile young infants presenting to emergency care. Design A planned secondary analysis within the Febrile Infants Diagnostic assessment and Outcome (FIDO) study, a prospective multicentre observational cohort study conducted across the UK and Ireland. Setting 35 paediatric emergency departments and assessment units across the UK and Ireland between 6 July 2022 and 31 August 2023. Patients Febrile infants aged 90 days and under presenting to emergency care. Main outcome measures IBI (meningitis or bacteraemia) among febrile infants, undergoing respiratory viral testing for respiratory syncytial virus (RSV), influenza and SARS-CoV-2. Results 1395 out of 1821 participants underwent respiratory viral testing, of those tested 339 (24.5%) tested positive for at least one of, SARS-CoV-2, RSV or influenza. A total of 45 infants (3.2%) were diagnosed with IBI. Of these
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Mashup Score: 1
Objective To describe the association of respiratory viral test results and the risk of invasive bacterial infection (IBI) for febrile young infants presenting to emergency care. Design A planned secondary analysis within the Febrile Infants Diagnostic assessment and Outcome (FIDO) study, a prospective multicentre observational cohort study conducted across the UK and Ireland. Setting 35 paediatric emergency departments and assessment units across the UK and Ireland between 6 July 2022 and 31 August 2023. Patients Febrile infants aged 90 days and under presenting to emergency care. Main outcome measures IBI (meningitis or bacteraemia) among febrile infants, undergoing respiratory viral testing for respiratory syncytial virus (RSV), influenza and SARS-CoV-2. Results 1395 out of 1821 participants underwent respiratory viral testing, of those tested 339 (24.5%) tested positive for at least one of, SARS-CoV-2, RSV or influenza. A total of 45 infants (3.2%) were diagnosed with IBI. Of these
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Mashup Score: 3Paediatric family activation rapid response (FARR) in acute care: a qualitative study for developing a multilingual application (app) intervention - 2 month(s) ago
Background Delayed recognition of clinical deterioration can result in harm to patients. Parents/carers can often recognise changes in the child’s condition before healthcare professionals (HCPs). To mitigate the risk of failure to rescue and promote early intervention, family-activated rapid response (FARR) systems are part of family-integrated care. Mechanisms for parents/carers to escalate concerns regarding their child’s clinical status remain limited to direct verbal communication, which may impede those with communication/linguistic challenges. Aim To develop a digital multilingual intervention by which families/carers can escalate their concerns directly to the rapid response team while in acute paediatric care. Methods A single-centre qualitative, co-design app development study was conducted. Evidence synthesis from a systematic review of the international literature informed interviews on intervention prototype development using co-design focus groups. Participant recruitment
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Mashup Score: 3Academic child health comes of age: lessons from the first 100 years of the first University Chair of Child Health in the UK - 2 month(s) ago
Academic paediatrics started by integrating medical care, scientific research, student teaching and clinical training. This model first appeared in Paris in 1803 at L’Hôpital des Enfants Malades,1 where dedicated staff treated children’s diseases while conducting research and teaching. Later, similar setups in Berlin, Vienna and Budapest further facilitated collaborative research, enabling systematic studies and laboratory investigations. The objective of this paper is to describe the development of academic paediatrics in Glasgow through the perspective of the first University Chair of Child Health in the UK. Glasgow established an academic department of child health with an endowed chair in 1924, modelled after Berlin’s paediatrics departments. The Samson Gemmell Chair of Medical Paediatrics was established by University of Glasgow, in memory of an Ayrshire doctor, Professor Samson Gemmell who had worked in the Children’s Hospital at Garnethill for many years in addition to his adult
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Mashup Score: 8Children’s voices and the climate crisis: a report from the RCPCH - 2 month(s) ago
The understanding of the extent and long-term magnitude of climate crisis continues to evolve. Alongside, there is ever-growing evidence that the crisis is having detrimental effects on children and young people’s (CYP) health and well-being. Beyond placing them at risk for a broad spectrum of diseases, it is challenging the very essence of CYP’s fundamental rights to survival, safety, good health, education and nutrition, as enshrined by the Convention on the Rights of the Child.1 2 The Royal College of Paediatrics and Child Health (RCPCH) is the membership body of paediatricians in the UK and its mission is to improve standards of care for children worldwide, by equipping paediatricians with skills and knowledge, shaping policy and advocating for child health issues. In 2020, the RCPCH declared a climate emergency. They formed a climate change working group and introduced a plan for action; to minimise the impact of climate crisis and promote a future which benefits CYP, including th
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Mashup Score: 0
In April 2024, the final report of the Cass Review, an independent review chaired by Dr Hilary Cass, was published, offering recommendations to improve gender identity services for children and young people in the UK. The core purpose of the Review was to improve care for children and adolescents. Commissioned by National Health Service England, the Review identified a weak evidence base for medical endocrine interventions and recommended that these treatments be provided within a structured research framework. The Review received widespread support from the clinical community. However, in July, the British Medical Association Council, without consulting its own members, unexpectedly passed a motion calling for a public critique of the Review, citing concerns over methodological weaknesses – a position it then softened following public criticism from members, concluding that their review would come instead from a position of neutrality. The original motion was based on two non-peer-rev
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Mashup Score: 7Mind the (preterm) gap: inequality in the UK’s current RSV immunisation approach will leave many preterm babies unprotected against RSV this winter - 2 month(s) ago
The UK Health Security Agency (UKHSA) recently announced respiratory syncytial virus (RSV) vaccination programmes to protect babies by vaccinating pregnant women at 28 weeks’ gestation, and older adults aged 75 and over.1 The decision, which offers infants protection from RSV for at least 6 months, is extremely welcome, supported by the Joint Committee on Vaccination and Immunisation (JCVI) recommendation in June 2023 (updated September 2023),2 and an open letter from the Royal College of Paediatrics and Child Health(RCPCH) in March 2024 urging policy implementation. The JCVI recommendation reviewed two products; first, infant immunisation through a single dose of anti-F protein extended half-life monoclonal antibody (nirsevimab, developed by Sanofi and AstraZeneca, marketed as Beyfortus), and second, maternal vaccination with a bivalent pre-fusion F protein (marketed as Abrysvo, manufactured by Pfizer). Both products were found to offer favourable RSV prophylaxis, leading to the Depar
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Mashup Score: 0Authors | Archives of Disease in Childhood - 2 month(s) ago
Editorial policies and instructions for authors looking to publish their work in Archives of Disease in Childhood.
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Viewpoint Mind the (preterm) gap: inequality in the UK’s current RSV immunisation approach will leave many preterm babies unprotected this winter @jeg_cworth https://t.co/aa2vFyRK22 https://t.co/K9Wd8fi0gm