Blood Advances is a semimonthly medical journal published by the American Society of Hematology. It is the first journal to join the Blood family in 70 years and is a peer-reviewed, online only, open access journal. Under the direction of founding editor-in-chief Robert Negrin, MD, Stanford University Medical Center, Stanford, CA, the inaugural issue debuted on November 29, 2016.
Abstract. DNMT3A mutations in patients with polycythemia vera were heterogeneous and not enriched in interferon alfa–treated patients. DNMT3A mutations had
In this issue of Blood, Takashima et al show that reduced STAT1 abundance in SRSF2-mutant myelodysplastic syndrome (MDS) cells confers protection against i
In this issue of Blood, Sklavenitis-Pistofidis et al use multiple large-scale screens to identify mantle cell lymphoma 1 (MCL1) and phosphatidylinositol 3-
Anna Azvolinsky, PhD, is a freelance medical and science journalist based in New York City. Point-of-care, commercial, rapid ADAMTS13 assays have recently been developed with…
Hematopoietic stem cells (HSCs) undergo profound changes over an organism’s life span, but tracking these age-related transitions has remained a challenge.
Key PointsThis nationwide study shows that major bleeding and thromboembolic events are more frequent in MF than previously described in other MPNs.The use
Key Points. Patients with large B cell lymphoma frequently experience infections within 100 days following CD19 CAR T-cell therapy.Infectious complications
Key PointsTriplet regimens provide longer TTNT and improved OS than doublets in Octos.The introduction of daratumumab-based regimens resulted in significan
Key PointsHigh surface expression of cMPL is a hallmark feature of LT-HSCs within the adult human CD34+ HSPC subset.Anti-cMPL immunotoxin selectively deple
Key PointsTriplet regimens provide longer TTNT and improved OS than doublets in Octos.The introduction of daratumumab-based regimens resulted in significan
