Headlines Expert Newsletters Covid-19 Specialties Trending Feeds Videos

Articles from: American Society of Hematology

Trending Latest

Mashup Score:4

American Society of Hematology

Trial in Progress: The Randomized, Double-Blind, Placebo-Controlled Phase Ib CROSSWALK-a Trial Evaluating the Safety of Crovalimab for the Management of Acute Uncomplicated Vaso-Occlusive Episodes (VOEs) in Patients with Sickle Cell Disease (SCD) - 13 hours

Mashup Score:4

Abstract. BackgroundSCD is a group of autosomal recessive red blood cell (RBC) disorders caused by a single point mutation in the β-globin gene, resulting...

  • 1597711656444129280 Profile photo of Madelyn
    Salvador Payán

    Hoy hemos tratado a un paciente, por primera vez en España, dentro del ensayo que valora la seguridad de #crovalimab,un inhibidor de C5, en el manejo de los episodios vasooclusivos en #drepanocitosis. Contento por contribuir a la construcción de evidencia https://t.co/SLQ98BnkrQ - view on twitter

More coverage: #crovalimab #drepanocitosis
See more from

Mashup Score:1

American Society of Hematology

Phenotypic heterogeneity in individuals with MECOM variants in 2 families - 18 hours

Mashup Score:1

TO THE...

More coverage: #clinicaltrialsandobservations #researchletter
See more from

Mashup Score:1

American Society of Hematology

Liver fibrosis and its response to avapritinib in 2 patients with systemic mastocytosis - 18 hours

Mashup Score:1

TO THE...

More coverage: #researchletter
See more from

Mashup Score:56

American Society of Hematology

First-in-human phase 1 trial of hemoglobin vesicles as artificial red blood cells developed for use as a transfusion alternative - 20 hours

Mashup Score:56

TO THE...

More coverage: #researchletter
See more from

Mashup Score:102

American Society of Hematology

North American Blastic Plasmacytoid Dendritic Cell Neoplasm Consortium: Position on Standards of Care and Areas of Need - 22 hours

Mashup Score:102

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy with historically poor outcomes and no worldwide consensus treatment...

More coverage: #bpdcn #leukemia #leusm
See more from

Mashup Score:1

American Society of Hematology

SAXS analysis of the intrinsic tenase complex bound to a lipid nanodisc highlights intermolecular contacts between factors VIIIa/IXa - 2 days

Mashup Score:1

Key Points. Biolayer interferometry and Michaelis–Menten enzyme kinetics support the formation of the active Xase complex on lipid nanodiscs.SAXS-derived...

More coverage: #thrombosisandhemostasis
See more from

Mashup Score:2

American Society of Hematology

conformational transition of the D′D3 domain primes von Willebrand factor for multimerization - 2 days

Mashup Score:2

Key Points. Magnetic tweezers reveal a pH-dependent destabilization of the D3 interface priming VWF for multimerization by exposing Cys1099 and Cys1142.The...

More coverage: #thrombosisandhemostasis #vascularbiology
See more from
American Society of Hematology

Development of a carotid artery thrombolysis stroke model in mice - 2 days

Key Points. Development of a mouse carotid artery thrombolysis model of stroke.iCAT enables assessment of adjunctive antithrombotic therapies on arterial...

More coverage: #thrombosisandhemostasis
See more from

Mashup Score:14

American Society of Hematology

Loss of α4A- and β1-tubulins leads to severe platelet spherocytosis and strongly impairs hemostasis in mice - 2 days

Mashup Score:14

Key Points. Platelets lacking α4A- and β1-tubulins are devoid of marginal band and fully spherical and inefficiently interact with matrices under flow.Mice...

See more from

Mashup Score:4

American Society of Hematology

Platelets: out of shape and misbehaving - 2 days

Mashup Score:4

The most prominent morphological feature of platelets is their unusual discoid shape from which they derive their name. But why do platelets have such...

See more from
Load More