Focal adhesions (FAs) form the junction between extracellular matrix (ECM)-bound integrins and the actin cytoskeleton and also transmit signals that regulate cell adhesion, cytoskeletal dynamics, and cell migration. While many of these signals are rooted in reversible tyrosine phosphorylation, phosphorylation of FA proteins on Ser/Thr residues is far more abundant yet its mechanisms and…
Light-harvesting complexes (LHCs) in photosynthetic organisms are attached to photosystem I (PSI), forming a PSI-LHCI supercomplex; however, it is unknown how LHCIs recognize their specific…
Background: Hypoxia can trigger the activation of blood platelets, leading to thrombosis. If not addressed clinically, it can cause severe complications and fatal consequences as…
Crossover interference is a phenomenon that affects the number and positioning of crossovers in meiosis and thus affects genetic diversity and chromosome segregation. Yet, the…
Competition is challenging to quantify in natural systems and inference is often made on indirect patterns of potential competition, such as trends in population trajectories…
Fluvial ecosystems are vital for biodiversity and human welfare but face increasing threats from flow intermittency caused by climate change and other human activities. To…
Excitation-inhibition (E/I) imbalance is theorized as a key mechanism in the pathophysiology of epilepsy, with a mounting body of previous research focusing on elucidating its…
Alzheimer’s disease (AD) is a neurodegenerative disorder with complex pathological manifestations and is the leading cause of cognitive decline and dementia in elderly individuals. A…
Environmental stressors present in the modern world can fundamentally affect humans’ physiology and health. Exposure to stressors like air pollution, heat, and traffic noise has…
In tomato clade, both self-incompatibility(S-) locus-dependent and -independent mechanisms are present in unilateral incompatibility (UI). Several stylar UI factors mediating S-locus-independent mechanism have been gradually…
Occupational exposure limit values (ELVs) for body internal electric fields can be derived from thresholds for action potential generation. These thresholds can be calculated with…
