Peripheral Artery Disease: Past and Future
Correspondence to: Mary M. McDermott, MD, Northwestern University Feinberg School of Medicine, 750 N Lake Shore Dr, 10th Floor, Chicago, IL 60611. Email Northwestern University Feinberg School of Medicine, Chicago, IL. Lower extremity peripheral artery disease (PAD) affects between 116 and 230 million people worldwide. 1 Manifestations of PAD range from asymptomatic, in which patients report no exertional leg symptoms, to chronic limb-threatening ischemia (CLTI), defined by lower-limb rest pain, gangrene,