Noncanonical inflammasome mediates BBB breakdown
Nature Reviews Immunology – Wei et al. report a role for membrane perforation mediated by gasdermin D pores in disruption of the blood–brain barrier.
Nature Reviews Immunology – Wei et al. report a role for membrane perforation mediated by gasdermin D pores in disruption of the blood–brain barrier.
Researchers at HMRI and the University of Newcastle have evaluated a drug called azithromycin, a macrolide antibiotic, to test if it would put moderate to…
Nature Communications – This study analyzes the embryonic replacement of maternally contributed mRNA with new mRNA in single cells and shows dynamic spatio-temporal regulation of…
B7H6 protein flags activated T cells for clearance by NK cells, and its genetic deletion enhances T cell proliferation and persistence.
Allergen exposure in wildling mice induces robust de novo responses and activates an endogenous memory TH2 cell pool.
Antiepileptic and anti-infectious agents were the most common classes tied to SJS-TEN.
Nature Reviews Endocrinology – Author Correction: Targeting the incretin system in obesity and type 2 diabetes mellitus
Allergist Dr. Dave Stukus and Allergic Living’s Gwen Smith offer insights on: the newly approved biologic food allergy treatment, epinephrine nasal sprays in…
Nature Communications – Sperm whales use sequences of clicks to communicate. Here, the authors show that these vocalizations are significantly more complex than previously believed-the…
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Nature – Our immune system falters over time, which could explain the negative effects of ageing.