Malaria vaccine introduction in Africa: progress and challenges
In 2024, Africa reached a pivotal milestone in its decades-long fight against malaria, a disease that has caused 94% of global cases and 95% of related deaths in Africa.1 Although global malaria mortality has substantially declined since 2000, the 2024 World Malaria Report2 revealed a concerning trend: the global malaria incidence rate was 58·6 cases per 1000 people at risk in 2023, indicating that progress towards the WHO Global Technical Strategy target of 21·3 cases per 10003 is off track. This is particularly concerning for the African Region, which bears a disproportionate malaria burden.
