Magnesium and ICH: More Work to Be Done
Studies have suggested a hemostatic role for magnesium in patients with intracerebral hemorrhage (ICH). A secondary analysis of the Field Administration of Stroke Therapy-Magnesium (FAST-MAG) trial did not show an association between treatment with magnesium and hematoma expansion (HE) or functional outcomes in patients with ICH. This analysis was confounded by imbalances in available data between the treatment and placebo groups and did not consider the effect of serum magnesium levels. Liotta et al.