Intravenous Alteplase in Patients With Minor Acute Ischemic Stroke — Where is the Limit?
Intravenous thrombolysis (IVT) is probably the most effective weapon for stroke physicians in acute ischemic stroke to achieve a better functional outcome. Guidelines and treatment recommendations evolved from a strict NIHSS > 3 points regime to a more liberal indication, namely the use in case of disabling symptoms, regardless of NIHSS-scoring. Guidelines do not recommend alteplase thrombolysis for patients with mild non-disabling symptoms (NIHSS 0 – 5). At least half of acute ischemic stroke patients