We may not think about it often, but our gut is home to a complex ecosystem of microorganisms that play a critical role in how we function. The system is delicate—one small change can cause a major shift in the microbiome, resulting in serious consequences. When a person takes an antibiotic, it can wipe out multiple bacterial species and throw this delicate balance off-kilter. Clostridioides…
Nature – Using single-cell DNA sequencing we show that most healthy women harbour rare populations of aneuploid epithelial cells with copy number alteration events in…
Nature Human Behaviour – In 394,005 UK individuals with exome sequencing data, Wu et al. find 56 neuroticism-associated genes (18 novel) and quantify the heritability…
Scientific Reports – The importance of including both sexes in preclinical sleep studies and analyses
Background The relationship between community-based healthcare barriers and risk of recurrent hospital-based care among persons with chronic liver disease (CLD) is understudied. We aimed to…
Nature Aging – Drivers of physiological aging are also linked to the etiology of chronic obstructive pulmonary disease (COPD), including inflammation and senescence, both influenced…
A study by researchers at the Icahn School of Medicine at Mount Sinai has identified strategies for using large language models (LLMs), a type of…
Nature Communications – RSV and hMPV infections pose significant health risks in vulnerable populations. Here, the authors used a systematic approach to identify mutations critical…
How do the functional networks in the brain change at the beginning of human life? This longitudinal perinatal fMRI study of 140 babies reveals regionally…
Results from a randomized, phase 2 clinical trial show that adding high-dose, intravenous (IV) vitamin C to chemotherapy doubles the overall survival of patients with…
Nature – Stable epigenetic changes indicate the existence of an obesogenic memory in mouse adipocytes that primes cells for pathological responses in an obesogenic environment…
