While SARS-CoV-2 infection has pleiotropic and systemic effects in some patients1–3, many others experience milder symptoms. We sought a holistic understanding of the severe/mild distinction in COVID-19 pathology, and its origins. We performed a whole-blood preserving single-cell analysis protocol to integrate contributions from all major cell types including neutrophils, monocytes, platelets,…
A role for vitamin D in immune modulation and in cancer has been suggested. In this work, we report that mice with increased availability of…
A role for vitamin D in immune modulation and in cancer has been suggested. In this work, we report that mice with increased availability of…
A role for vitamin D in immune modulation and in cancer has been suggested. In this work, we report that mice with increased availability of…
Despite deep knowledge of how the immune system works, many questions remain difficult to answer within the current core framework of innate and adaptive immunity.…
Exercise has long been acknowledged for its powerful disease-preventing, health-promoting effects. However, the cellular and molecular mechanisms responsible for the beneficial effects of exercise are…
Calorie restriction and intermittent fasting both increase longevity in animals, aging experts say. Here’s what that means for you.
Current understanding of the heterogeneity of post-acute COVID-19 syndrome (PACS) is limited. Examining the fecal microbiome in subjects with PACS, Su et al. uncover an association…
Nature – Topobiologically complex mini-colons—which enable the faithful in vitro recapitulation of colorectal cancer tumorigenesis and its environmental determinants—offer the…
Recent approvals of exa-cel for treatment of sickle cell disease and transfusion-dependent β-thalassemia mark the dawn of the era of gene editing in medicine. But…
Recent approvals of exa-cel for treatment of sickle cell disease and transfusion-dependent β-thalassemia mark the dawn of the era of gene editing in medicine. But…
