Few effective therapeutic options are available for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. IL-6 receptor blockade has been proposed as one potential therapeutic strategy, and more than 40 clinical trials of anti-IL-6 receptor antibodies (including tocilizumab and sarilumab) in the setting of SARS-CoV-2 infection are underway (appendix p 2). Early…
Two conventional synthetic DMARD tapering strategies were associated with significantly lower rates of flare-free survival compared with stable conventional synthetic DMARD treatment, and the data…
Little is known about the natural course and long-term outcomes of childhood-onset Sjögren’s disease due to its low prevalence, difference in clinical presentation between children…
The Florida Scoring System is a paediatrician-friendly tool that can be used to assist classification and long-term monitoring of suspected childhood Sjögren’s disease. The resulting…
Debashish Danda, professor of rheumatology and immunology at Narayana Health Institute, Bengaluru, India, died on Feb 23, 2024. He had an illustrious career as a…
Debashish Danda, professor of rheumatology and immunology at Narayana Health Institute, Bengaluru, India, died on Feb 23, 2024. He had an illustrious career as a…
Explore clinical research, expert reviews, and comment and opinion from The Lancet Rheumatology. A voice for rheumatology specialists worldwide
Participants adhered well to the non-operative interventions and their health-related quality of life improved. Participant and health professional feedback were extremely positive. These findings support…
In patients where antidrug antibodies were detected, remission was less likely to be reached and sustained, and infusion reaction or discontinuation of infliximab was more…
On March 11, 2024, Seattle Children’s Hospital (Seattle, WA, USA) announced that it had received approval from the US Food and Drug Administration for a…
In adults undergoing total hip arthroplasty, a combination of paracetamol, ibuprofen, and dexamethasone had the lowest morphine consumption within 24 h following surgery and the…
