Approximately two-thirds of small, indeterminate lesions of the testes might be benign and not require radical orchidectomy. Management strategies are evolving to include vigilant active surveillance and excisional biopsy of the lesion with further management guided by histological outcome.
In prostate cancer (PCa), questions remain on indications for prostate-specific membrane antigen (PSMA) positron emission tomography (PET) imaging and…
In prostate cancer (PCa), questions remain on indications for prostate-specific membrane antigen (PSMA) positron emission tomography (PET) imaging and…
Pembrolizumab plus lenvatinib has shown antitumor activity and acceptable safety in patients with platinum-refractory urothelial carcinoma (UC).To eva…
This genetic association study examines the association between variants of established prostate cancer risk genes and the risk of aggressive prostate cancer.
A paper in Science reports a time-resolved multiomic atlas of the human yolk sac, expanding knowledge of this poorly resolved structure in humans.
Roohani et al. have developed a deep learning tool called GEARS that predicts the effects of multigene perturbations.
Genome-wide association studies (GWAS) have revealed important biological insights into complex diseases. The authors review approaches that leverage GWAS to identify opportunities for repurposing existing…
Carla Daniela Robles-Espinoza celebrates a paper that inspired a new generation of Mexican scientists.
Background Treatment decisions for localized prostate cancer must balance patient preferences, oncologic risk, and preservation of sexual, urinary and bowel function. While Active Surveillance (AS)…
2-aminothiazole — a hybrid of prebiotic amino acid and nucleotide precursors — sequentially accumulates and purifies glycolaldehyde and glyceraldehyde from complex mixtures in the order…
