ApoE2 and ApoE Christchurch variants are defective in LDLR binding, thus reducing the uptake of ApoE and associated lipid cargoes. LDLR-mediated internalization and endolysosomal delivery of ApoE lipoprotein particles carrying cholesterol esterified with polyunsaturated fatty acids result in lipofuscin deposition with the allelic series ApoE2 < ApoE3 < ApoE4.
Reports of rising hMPV infections in China have attracted media attention, but experts say the virus poses low pandemic risk owing to widespread immunity.
The company has been working on it for nearly 10 years.
Officials sent a follow-up alert shortly after.
Several viral videos and images appeared to be taken with drones in conflict with a temporary flight restriction (TFR) issued by the Federal Aviation Administration…
Some health systems are hesitant to invest in programs that provide hospital-level care at home without a long-term extension of the Medicare waiver.
Ai Me is a cute baby robot unveiled at CES that can be your kid’s best buddy. It can protect your house, manage devices, and…
Romanian startup .lumen is transforming mobility for the visually impaired with innovative glasses that combine self-driving technology and haptic guidance to replicate the essential functions…
At CES 2025, Brelyon showed off its latest immersive monitor that uses 1-bit of monocular depth to create a display that looks bigger and deeper…
Hernia – Available reports of surgeon efficiency when transitioning from laparoscopic to robotic-assisted (RA) inguinal hernia repair (IHR) are retrospective or describe single-center experience….
Hernia – Surgical treatment of inguinal hernias in children is one of the most common operative procedures worldwide. During surgery for inguinal hernias in adults, chronic…
