Startle epilepsy, characterized by startle-provoked epileptic seizures, was historically recognized as one of the reflex epilepsies but currently lacks classification as a specific epileptic syndrome because of insufficient characterization. This study …
Under the umbrella of the Brain Health Mission, and as a way to support its 48 National Neurological Societies , EAN has developed online Advocacy…
Background: Little is known about how multiple sclerosis (MS) presents in Hispanic/Latinx (HL) people with MS (pwMS). Objective: Compare age at onset (AAO) and …
Background: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that, when untreated, can lead to significant disability in young a…
Background: In Europe, ofatumumab is approved for breastfeeding, but data on its transfer into breast milk and clinical experience are lacking. Objective: To an…
Background: Real-world studies are needed to expand our knowledge concerning populations underrepresented in clinical trials. Objective: This study aimed to eva…
Nature Communications – An expansion of a hexanucleotide repeat in the C9ORF72 gene can cause ALS. Here, the authors develop a high-fidelity RNA-targeting CRISPR system…
Nature Aging – The authors show that neuroprotective and neurotoxic astrocytes represent transitional cellular substates present during neuroinflammation and that targeting mTOR in astrocytes…
The benefits of early initiation of disease-modifying therapy in multiple sclerosis are well-established; however, the issue of when and how to de-escalate
FSHD type 1 shows marked variability in age at onset and disease severity. Zheng et al. reveal independent contributions of genetic characteristics, includ
Delva et al. show that blood-based tests for Alzheimer’s disease biomarkers—specifically the plasma Aβ42/40 ratio and pTau181—can be used to predict conver
