Multiple sclerosis leads to smoldering inflammation in the central nervous system upheld by proliferating immune cells, including B cells; however, current therapies remain insufficient to target these immune compartments. Here, CD19-targeted CAR-T cell therapy was applied in two patients with multiple sclerosis, showing tolerable safety with promising disease-specific target-cell effects.
Also known as Willis-Ekbom disease, restless legs syndrome usually occurs in the evening or at night when a person has been sitting or lying down.…
Are emulation ‘trials’ helpful, despite the biases that occur with observational data, or do they truly mimic the results of randomized controlled trials (RCTs)?
As we mark our recent 2,400th robotic mitral valve repair, surgeons reflect on how they’ve achieved a 99.7% repair rate and operative mortality of 0.04%.
In this issue of Cancer Cell, Qiu et al. use single-cell metabolic analysis to identify reduced mannose metabolism as a previously unknown feature of exhausted T cells.…
Lack of uniform standards for medical records and algorithms is impeding widespread adoption of health AI, a Congressional task force said.
This week, the FDA granted clearance to Withings’ BPM Pro 2 cellular blood pressure monitor. The device seeks to help providers scale remote patient monitoring…
Stomach cancer can make eating difficult in unexpected ways. But it’s crucial you continue getting the nutrients your body needs. A general surgeon explains how…
AI Claims Amid the fallout from UnitedHealthcare CEO Brian Thompson’s murder, the firm’s prescription drug middleman is under fire for a huge AI oopsie. As…
Lou et al. engineered source-sink relations to improve carbon partitioning by targeted insertion of heat-shock cis-elements into cell-wall-invertase genes using prime editing. This delivers climate-smart crops…
The tool will initially be available in South Florida and New York City.
