Androgen conspires with the CD8+ T cell exhaustion program and contributes to sex bias in cancer
Cell-intrinsic androgen receptor signaling promotes the male-biased susceptibility of CD8+ T cells to functional exhaustion in tumors.
Cell-intrinsic androgen receptor signaling promotes the male-biased susceptibility of CD8+ T cells to functional exhaustion in tumors.
Structural and functional MRI reveals brainstem connections that sustain wakefulness, a key component of human consciousness.
Recent studies have uncovered a new role for sensory neurons in influencing mammalian host immunity, challenging conventional notions of the nervous and immune systems as…
As restrictions take effect, new data show virus is pervasive in herds
Mulè et al. provide a framework for integrating human population and single-cell variations to study vaccine responses with and without the adjuvant AS03. They uncover AS03-specific…
T cells release a cytokine that stimulates changes to their metabolism during differentiation.
Department of Energy funds research to take carbon out of iron and steel production
Quantitative analysis of biodistribution and clearance may improve nanoparticle development
Thomas Südhof says mistakes in co-authored publications are honest errors that don’t affect studies’ conclusions
Structural and functional MRI reveals brainstem connections that sustain wakefulness, a key component of human consciousness.
Multilayered gene regulation orchestrates cell-type-specific cytokine expression. Liu et al. examine the impact of chromatin loop formation on the expression of IFN-γ and IL-22, which are…