Herd Immunity: Understanding COVID-19
What does herd immunity mean? Here, we explain basic concepts of herd immunity and discuss its implications for COVID-19 in a whiteboard video based on the I…
What does herd immunity mean? Here, we explain basic concepts of herd immunity and discuss its implications for COVID-19 in a whiteboard video based on the I…
Interrogating data of monozygotic twins discordant for multiple sclerosis (MS), Ingelfinger et al. identify decreased frequency of blood CXCR3+ B cells as a non-inheritable feature in…
Tenggara et al. use a single-cell-derived antibody supernatant analysis (SCAN) workflow to efficiently generate quantitative BCR neutralizing IC50 data against HIV-1, on top of which a…
The Xist RNA protein complex, present only in females, is immunogenic and may underlie female-biased autoimmunity.
Tricarboxylic acid (TCA) cycle metabolites have been implicated in modulating signalling pathways in immune cells. Notable examples include succinate and itaconate, which have pro- and…
We report on the relationship between leukocyte telomere length (LTL), genetics, and environmental factors in ethnically diverse Africans. LTL is longer in African ancestry individuals…
STAR Protocols is an open access, peer-reviewed journal from Cell Press. We offer structured, transparent, accessible, and repeatable step-by-step experimental and computational protocols from all…
OA was generally considered as a non-inflammatory disease dominated by articular cartilage degeneration. However, the role of synovitis in OA pathogenesis has received increasing attention.…
Polyamines – putrescine, spermidine, and spermine – are widely distributed aliphatic compounds known to regulate important biological processes in prokaryotic and eukaryotic cells. Therefore, spermidine…
The intestinal epithelium fulfills important physiological functions and forms a physical barrier to the intestinal lumen. Barrier function is regulated by several pathways, and its…