Fu et al. discover a non-metabolic function of TKT in gliomas. Mechanistically, TKT undergoes translocation from the cytoplasm to the nucleus following chemotherapy. Nuclear TKT interacts with XRN2 to prevent excessive R-loop accumulation, while depletion of TKT leads to increased R-loop accumulation and genome instability, potentiating chemotherapy efficacy.
Making integrated fracture liaison services a routine part of postfracture care could help reduce disparities in care — and may offer a useful model for…
Respiratory syncytial virus (RSV) season often starts in the fall and peaks in winter. RSV vaccines are available to help reduce risk for severe illness.
You may forget about your gums sometimes. But healthy gums are just as important as healthy teeth. Here’s how to know if your gums are…
Case of a 38-year-old who beat the odds against the 90% fatality rate for grade 5 brain aneurysm and has returned to many daily activities.…
The list of 15 more of the priciest medications selected for the negotiation program is supposed to be released by Feb. 1.
A state-by-state breakdown of over 80 acute care hospital projects announced, initiated, or opened in 2024.
Vertex’s leaders projected confidence in the firm’s non-opioid pain franchise at the JP Morgan Healthcare Conference on Monday, although the first cut of data for…
Fewer giant deals, but many more smaller ones, in bit barn feeding frenzy
– Statistically significant mean weight loss of 22.8% (21.1% placebo adjusted) at 36 weeks; 59% of HRS9531-treated participants lost 20% or more of their baseline…
In this eight-part, eye-opening docuseries ReThink Meat, we explore the environmental impact of sustainable, regenerative livestock farming. With insights fr…
