Boo and Shin et al. uncover that the EJC deposited onto circRNAs after back-splicing is spatially located near the 3′ UTR of mRNA through circRNA-mRNA interaction. The EJC on circRNA triggers NMD of the mRNA. Mechanistic studies reveal the roles of circNMD in apoptosis and its therapeutic potential for mRNA downregulation.
Nature – A phase I trial of a neoantigen-targeting personalized cancer vaccine led to durable and polyfunctional T cell responses and antitumour recognition, and was…
The president abandoned Anthony Tata’s nomination for a top policy job during his first term due to Senate resistance.
The Year in Review in Oncology 2024 brought to you by some of the Worlds TOP experts!
All nine patients treated at Dana-Farber Cancer Institute in a phase 1 trial of a personalized cancer vaccine for patients with stage III or IV…
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In-basket message interactions play a crucial role in physician-patient communication, occurring during all phases (pre-, during, and post) of a patient’s care journey. However, responding…
The Year in Review in Oncology 2024 brought to you by some of the Worlds TOP experts!
2024 was a year of breakthroughs in cancer care, research and knowledge at Ohio State, where oncology experts look ahead to opportunities to innovate in…
The Year in Review in Oncology 2024 brought to you by some of the Worlds TOP experts!
Speaker: Karina Wilkerson Karina Wilkerson is the Program Coordinator of the Adult Sickle Cell of Excellence Program at Vanderbilt University Medical Center where she leads…
