Gliocidin is a nicotinamide-mimetic prodrug that targets glioblastoma
Nature – The prodrug gliocidin effectively kills glioblastoma cells by targeting de novo purine synthesis, improving survival in mouse models.
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Trends in breast cancer specific death by clinical stage at diagnoses between 2000-2017
AbstractBackground. Approximately 40,000 individuals die from metastatic breast cancer each year. We examined what fractions of annual breast cancer-specif
Rapid biphasic decay of intact and defective HIV DNA reservoir during acute treated HIV disease
Nature Communications – HIV reservoir decay is less well studied in acute infection. Here, the authors show that reservoir decay rates are biphasic and 5x…
At Massachusetts General Hospital, work is well underway on new $1.9 billion clinical care facility – The Boston Globe
The Phillip and Susan Ragon Building will house the Mass General Cancer Center and the Corrigan Minehan Heart Center, with 482 single-bed rooms and other…
Persistent challenges with treating multiple myeloma early.
Author(s): Goodman, Aaron M; Kim, Myung S; Prasad, Vinay | Abstract: Over the past decade, 2 strategies have advanced the treatment of patients with multiple…
The OncoAlert5k at SABCS24
Warm invite to come for a healthy outing in front of the Alamo, we will take in the beauty of the riverwalk and get our…
Predicting Structural Consequences of Antibody Light Chain N-Glycosylation in AL Amyloidosis
Background/Objectives: Antibody light chains form amyloid fibrils that lead to progressive tissue damage in amyloid light chain (AL) amyloidosis. The properties of each patient’s unique…
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American Nazis Rally in New York City
On February 20, 1939, the pro-Nazi German American Bund drew more than 20,000 people to a rally in Madison Square Garden.
US Holocaust Museum’s “early warning signs of fascism” sign is going viral
Those who don’t know their history are doomed to repeat it. And one of the country’s Holocaust museums wants to make sure that fascism doesn’t make a…