Pressure Overload–Induced Cardiac Hypertrophy Stimulates Tumor Growth in Tumor-Prone ApcMin Mice
Correspondence to: Rudolf A. de Boer, MD, PhD, Department of Cardiology, Erasmus MC, Dr Molewaterplein 40, 3015 GD, Rotterdam, the Netherlands. Email Heart failure (HF) and cancer are leading causes of death worldwide and often coincide. A growing number of epidemiological studies have shown that patients with HF are at increased risk of cancer. 1 Providing mechanistic proof for these observations, preclinical studies have shown that HF stimulates tumor growth in mouse HF-cancer models. 1–4 Several