Increased Functional Connectivity Characterises the Prodromal Phase of the Migraine Cycle

Episodic migraine is reflected by cyclic changes in behaviour and cortical processing. In this study, we aimed to identify how functional connectivities change over the entire migraine cycle. By using longitudinal neuroimaging and a whole-brain analysis approach, we tested 12 episodic migraine patients across 82 fMRI recordings during spontaneous headache attacks, with follow-up measurements over…

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