The role of cargo receptors in proinsulin export from the ER is unclear. Here, the authors identify the WFS1 protein, which is mutated in Wolfram syndrome and associated with diabetes, as an ER to Golgi cargo receptor required for normal insulin processing and secretion.
Nature Communications – Researchers test geodynamic models for far-field continental deformation during the Laramide orogeny. New and existing thermal data show that the hot hinterland…
In this webinar, our panelists will discuss recent developments and challenges for adoptive cell therapies for cancer treatment. Our spea…
Nature Communications – Bacteria have evolved various defence mechanisms to protect themselves against viral infection. Here, Patel et al. identify a type of antiviral defence…
Nature Communications – Decarbonizing the European ammonia industry: Less stringent emissions caps for electrolytic hydrogen production can significantly reduce costs and land use while still…
Nature Communications – A hindcast experiment of the 2021 summer flood in West Germany unveils a 17-hour lead time for preparedness and advisable action, holding…
Nature Communications – The average Internet user spends over 40% of their waking hours online, yet the environmental footprint remains poorly understood. This study suggests…
Nature Communications – Human Papillomaviruses (HPV) are classified in lineages based on their sequence. Here, the authors test neutralizing activity of sera from naturally infected…
Nature Communications – Interaction with surrounding lumina leads to potential medical risks in transluminal procedures. Here, the authors report a magnetic steering continuum robot that…
Nature Communications – Finding an optimal shape for transport networks, represented as multilayer structures, is a challenging problem. The authors propose analytical and computational frameworks…
Nature Communications – The cell-wall peptidoglycan in model bacteria typically includes 4,3- and 3,3-crosslinks, catalysed by DD- and LD-transpeptidases, respectively. Here, the authors identify…
