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Biology and Management of Acute Myeloid Leukemia With Mutated NPM1
Mutations in nucleophosmin 1 (NPM1) are diseased-defining genetic alterations encountered in approximately one-third of cases of acute myeloid leukemia (AML). A mutation in NPM1 confers…
A family’s fight against Ewing sarcoma sparks breakthrough cancer research at Cleveland Clinic
Diagnosed with Ewing sarcoma at 9, Lucy Spada beat the odds and survived. Her family started the Little Warrior Foundation to help other pediatric cancer…
Sasha’s Hope: Cleveland Clinic works on breakthrough cancer vaccine for kids
A 12-year-old Atlanta girl has turned to Cleveland researchers for treatment of her Ewing Sarcoma, and the hope a breakthrough vaccine is on the way.
Live updates: Judge temporarily blocks Trump plan offering incentives for federal workers to resign
A federal judge has blocked President Donald Trump’s plan to push out federal employees by offering them financial incentives. The ruling came hours before the…
Elon Musk’s DOGE is feeding sensitive federal data into AI to target cuts
Department of Government Efficiency workers embedded in the Education Department have been processing sensitive agency data using artificial intelligence.
Fixed-Duration Acalabrutinib Combinations in Untreated Chronic Lymphocytic Leukemia | NEJM
Whether fixed-duration acalabrutinib–venetoclax (with or without obinutuzumab) would result in better progression-free survival than chemoimmunotherapy in patients with untreated chronic lymphocyti…
2024 was an incredible year of innovation for our Division of Pediatric… | Cleveland Clinic Children’s
2024 was an incredible year of innovation for our Division of Pediatric Hematology & Oncology! We’re proud to share some of our key accomplishments from…
Efficacy of Zenocutuzumab in NRG1 Fusion–Positive Cancer | NEJM
Neuregulin 1 (NRG1) fusions are recurrent oncogenic drivers found in multiple solid tumors. NRG1 binds to human epidermal growth factor receptor 3 (HER3), leading to…
Michael McFaul: You know who shut down USAID when I was in Russia? Putin did
Fmr. Amb. Michael McFaul, Mara Gay and Chris Matthews discuss the president’s call to shut down USAID and to take control of Gaza.
Asciminib plus dasatinib and prednisone for Philadelphia chromosome–positive acute leukemia
Key PointsDasatinib, asciminib, and prednisone can be safely combined for the dual targeting of BCR::ABL1 in Ph+ acute leukemia.Dasatinib and asciminib com
