Unraveling a Key Molecular Player Governing Pulmonary Alveolar Development
Secondary septa formation is a crucial process in the development of pulmonary alveoli, the small air sacs in the lungs where gas exchange occurs. During the alveolar stage of lung development, secondary septa form via the creation of new alveolar structures from existing primitive septa (1). This results in an increase in the surface area available for gas exchange. The formation of secondary septa is driven by complex cellular and molecular events orchestrated by multiple signaling pathways and cell