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Mashup Score: 156Proximity-dependent labeling identifies dendritic cells that drive the tumor-specific CD4+ T cell response - 1 month(s) ago
This study characterizes the dendritic cells that present antigen to tumor-specific CD4+ T cells in the tumor and tumor-draining lymph node.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 107Oncogenic KRAS drives immunosuppression of colorectal cancer by impairing DDX60-mediated dsRNA accumulation and viral mimicry - 1 month(s) ago
KRAS disrupts dsRNA homeostasis and impairs viral mimicry by suppressing DDX60 via the AKT/GSK3β/STAT3 pathway.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
New research in Science #Immunology reports that oncogenic #KRAS promotes immune evasion in #colorectal cancer cells by increasing double stranded DNA degradation and inhibiting interferon responses. https://t.co/6pkawilDip https://t.co/nAeTKTfRD0
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Mashup Score: 79Maintenance of X chromosome inactivation after T cell activation requires NF-κB signaling - 1 month(s) ago
X chromosome inactivation maintenance, including Xist RNA localization to the inactive X, requires canonical NF-κB signaling in T cells.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
New research suggests that #NFκB signaling is necessary to maintain #Xchromosome inactivation after T cell activation. Read more in Science #Immunology: https://t.co/eZ82Mhz6Sg @montserrat @pennvet https://t.co/VFPNTXJ4Cd
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Mashup Score: 150Proximity-dependent labeling identifies dendritic cells that drive the tumor-specific CD4+ T cell response - 1 month(s) ago
This study characterizes the dendritic cells that present antigen to tumor-specific CD4+ T cells in the tumor and tumor-draining lymph node.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
A new study in Science #Immunology highlights how LIPSTIC, a proximity-based labeling method, can identify antigen-presenting #DendriticCells that activate #CD4+ TCells in the tumor and tumor-draining lymph nodes in mice. https://t.co/y1rqq6hYln @ChudnovskiyLab @victora_lab https://t.co/hPIBXyZ57X
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Mashup Score: 102Oncogenic KRAS drives immunosuppression of colorectal cancer by impairing DDX60-mediated dsRNA accumulation and viral mimicry - 1 month(s) ago
KRAS disrupts dsRNA homeostasis and impairs viral mimicry by suppressing DDX60 via the AKT/GSK3β/STAT3 pathway.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
New research in Science #Immunology reports that oncogenic #KRAS promotes immune evasion in #colorectal cancer cells by increasing double stranded DNA degradation and inhibiting interferon responses. https://t.co/6pkawilDip https://t.co/nAeTKTfRD0
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Mashup Score: 68Maintenance of X chromosome inactivation after T cell activation requires NF-κB signaling - 1 month(s) ago
X chromosome inactivation maintenance, including Xist RNA localization to the inactive X, requires canonical NF-κB signaling in T cells.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
New research suggests that #NFκB signaling is necessary to maintain #Xchromosome inactivation after T cell activation. Read more in Science #Immunology: https://t.co/eZ82Mhz6Sg @montserrat @pennvet https://t.co/VFPNTXJ4Cd
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Mashup Score: 151Contents | Science Immunology 9, 100 - 2 month(s) ago
ONLINE COVER Sex-Biased Gene Regulation in T Cells. In females, X chromosome inactivation (XCI) represses gene expression from one X chromosome to balance gene dosage between the sexes. This process is controlled by the long noncoding RNA Xist, which coats the inactive X chromosome and promotes epigenetic gene silencing. Forsyth et al. studied XCI in mouse and human T cells, a process that is much more dynamic in T cells than in most other somatic cells. NF-κB signaling downstream of the T cell receptor
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Science #Immunology's October issue is out! This month's cover highlights how #NFkB signaling helps recruit the noncoding RNA Xist to maintain #XChromosomeInactivation in activated T cells. Read this research and more: https://t.co/sfmAjsRlhs https://t.co/x7cQ9xfZOj
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Mashup Score: 29HDAC3 integrates TGF-β and microbial cues to program tuft cell biogenesis and diurnal rhythms in mucosal immune surveillance - 2 month(s) ago
HDAC3 integrates gut luminal cues to program intestinal tuft cell diurnal biogenesis and immune surveillance via TGF-β signaling.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
New research in mice suggests that intestinal #TuftCell numbers fluctuate with #circadian and feeding patterns to prepare for potential food-borne pathogens. Read more in Science #Immunology: https://t.co/erG4xEg6Z1 @CMU_Bio https://t.co/CrMoP1CblG
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Mashup Score: 219Twin study identifies early immunological and metabolic dysregulation of CD8+ T cells in multiple sclerosis - 2 month(s) ago
Proinflammatory features of CD8+ T cells in multiple sclerosis may serve as potential therapeutic targets in both prodromal and definitive stages.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Cytotoxic #Tcells have distinct pro-inflammatory signatures in people with #MultipleSclerosis, according to a new twin study in Science #Immunology. https://t.co/ohwRoJZHLg https://t.co/S8volVOIq8
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Mashup Score: 29HDAC3 integrates TGF-β and microbial cues to program tuft cell biogenesis and diurnal rhythms in mucosal immune surveillance - 2 month(s) ago
HDAC3 integrates gut luminal cues to program intestinal tuft cell diurnal biogenesis and immune surveillance via TGF-β signaling.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
New research in mice suggests that intestinal #TuftCell numbers fluctuate with #circadian and feeding patterns to prepare for potential food-borne pathogens. Read more in Science #Immunology: https://t.co/erG4xEg6Z1 @CMU_Bio https://t.co/CrMoP1CblG
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A new study in Science #Immunology highlights how LIPSTIC, a proximity-based labeling method, can identify antigen-presenting #DendriticCells that activate #CD4+ TCells in the tumor and tumor-draining lymph nodes in mice. https://t.co/y1rqq6hYln @ChudnovskiyLab @victora_lab https://t.co/hPIBXyZ57X