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Mashup Score: 45A tetraspecific engager armed with a non-alpha IL-2 variant harnesses natural killer cells against B cell non-Hodgkin lymphoma - 18 day(s) ago
IPH6501, a CD20-targeted NK cell engager armed with non-alpha IL-2, shows preclinical efficacy and tolerability in B-NHL.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 106Stem-like memory and precursors of exhausted T cells share a common progenitor defined by ID3 expression - 18 day(s) ago
ID3 defines stem-like T cells with high developmental potential that sustain T cell responses to chronic infection and cancer.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Scientists have identified #ID3 as marker for #StemLike T cells that sustain immune responses to chronic infection and cancer. @JohnstoneRicky @KalliesLab @UniMelb Read more in Science #Immunology: https://t.co/0F87vWeC3B https://t.co/gbyBjdNgtM
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Mashup Score: 270Trogocytosis of chimeric antigen receptors between T cells is regulated by their transmembrane domains - 19 day(s) ago
Chimeric antigen receptor trogocytosis transfers antitumor immunity between T cells and is dictated by their transmembrane domain.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Researchers have demonstrated that #CARTcells can transfer tumor-specific receptors to T cells in mice via #trogocytosis, endowing recipient cells with antitumor immunity. @UU_University Read more in Science #Immunology: https://t.co/KDdfundeoJ https://t.co/hPnYzvNbbX
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Mashup Score: 100Stem-like memory and precursors of exhausted T cells share a common progenitor defined by ID3 expression - 22 day(s) ago
ID3 defines stem-like T cells with high developmental potential that sustain T cell responses to chronic infection and cancer.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Scientists have identified #ID3 as marker for #StemLike T cells that sustain immune responses to chronic infection and cancer. @JohnstoneRicky @KalliesLab @UniMelb Read more in Science #Immunology: https://t.co/0F87vWeC3B https://t.co/gbyBjdNgtM
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Mashup Score: 63Coordinated immune networks in leukemia bone marrow microenvironments distinguish response to cellular therapy - 24 day(s) ago
Response to donor lymphocyte infusion in AML is characterized by marrow immunological diversity and clonal expansion of CD8+ cytotoxic T cells.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
New research suggests that the bone marrow microenvironment in patients with relapsed acute myeloid #leukemia can affect response to donor lymphocyte infusion therapy. @DanaFarber @elhamazizi @Dr_KatieM @Columbia Learn more in Science #Immunology: https://t.co/vLFZXD0QkH https://t.co/x6Llet5QHe
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Mashup Score: 12
Antibodies targeting the influenza hemagglutinin from potentially pandemic H5Nx viruses can be isolated from naïve individuals.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
A new Science #Immunology study finds that humans without known exposure to bird flu have #antibodies that can recognize H5-specific hemagglutinin and neutralize highly pathogenic #H5N1. @gogo_science @SchmidtLabHMS https://t.co/5fN7c52nxZ https://t.co/KNlDDl1Oz2
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Mashup Score: 48Coordinated immune networks in leukemia bone marrow microenvironments distinguish response to cellular therapy - 26 day(s) ago
Response to donor lymphocyte infusion in AML is characterized by marrow immunological diversity and clonal expansion of CD8+ cytotoxic T cells.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
New research suggests that the bone marrow microenvironment in patients with relapsed acute myeloid #leukemia can affect response to donor lymphocyte infusion therapy. @DanaFarber @elhamazizi @Dr_KatieM @Columbia Learn more in Science #Immunology: https://t.co/vLFZXD0QkH https://t.co/x6Llet5QHe
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Mashup Score: 12
Antibodies targeting the influenza hemagglutinin from potentially pandemic H5Nx viruses can be isolated from naïve individuals.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
A new Science #Immunology study finds that humans without known exposure to bird flu have #antibodies that can recognize H5-specific hemagglutinin and neutralize highly pathogenic #H5N1. @gogo_science @SchmidtLabHMS https://t.co/5fN7c52nxZ https://t.co/KNlDDl1Oz2
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Mashup Score: 180
DC–T cell interactions during priming influence CD8+ T cell fate, and DCs subsequently sustain T cell responses against cancer.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
A new Science #Immunology Review highlights the role of #DendriticCells in shaping T cell antitumor responses and explores how this interplay could be harnessed for cancer #vaccines. https://t.co/e4KsjJoD1r https://t.co/nHRHNGl73D
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Mashup Score: 40Anti–immune complex antibodies are elicited during repeated immunization with HIV Env immunogens - 1 month(s) ago
Polyclonal epitope mapping reveals anti–immune complex antibodies that target idiotopes on antibodies bound to HIV Env.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Repeated #HIV immunizations in rabbits and rhesus macaques can induce anti-idiotypic #antibodies that target anti-HIV antibodies generated by previous immunizations. @WardLab1 @SharidanBrown @scrippsresearch Read more in Science #Immunology: https://t.co/decqQddh1i https://t.co/kGxLYok42N
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New preclinical research from @EricVivier1 highlights the promise of #NaturalKillerCell engagers that induce antitumor activity against B cell non-Hodgkin #lymphoma. @DemariaO More in Science #Immunology: https://t.co/ZrkBnYnWsw https://t.co/jI0azWJbuz