• Mashup Score: 1

    This meta-analysis evaluates the difference in all-cause and cause-specific mortality in randomized clinical trials comparing percutaneous coronary intervention with coronary artery bypass grafting for the treatment of patients with coronary artery disease.

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    • RT @AlborsJose: Mortality in Randomized Clinical Trials Comparing PCI With CABG https://t.co/WuEPlCPscq vía @JAMAInternalMed part of @JAMAN…

  • Mashup Score: 4

    Footage exclusively obtained by the BBC shows people huddling together in a stranded cable car.

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    • When one's life is literally dangling on a rope..... Wonder what these passengers must have been experiencing.... Couldn't even envisage! @DocSavageTJU @cardiojaydoc02 @AliRacaniere @MD_ChaudhryH @BartoszHudzik @BirkhoelzerS @Vilavaite @Argenscore https://t.co/izYiwEdwhq

  • Mashup Score: 9
    Individual response - 9 month(s) ago

    I can see how important patient/treatment qualitative interactions could be missed as a result of poor RCT design (e.g., inappropriate “lumping” of patients in disparate clinical states into a single trial). Failure to do adequate preparatory study to optimize disease definition, trial inclusion criteria, and measurement tools would be analogous to a drug company skipping preclinical or early phase clinical studies and jumping to phase III- the chance of success would be very low (see below). I…

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    • RT @f2harrell: Great discussion at https://t.co/nvDWNyxfyR . "the counterfactual approach requires a faithful belief in metaphysical obje…