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Mashup Score: 0Clinical trials for pig-to-human organ transplants inch closer - 2 year(s) ago
US regulatory agency signals willingness to allow first xenotransplant trials.
Source: www.nature.comCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 2Astronomy Photographer of the Year 2022 shortlist revealed - 2 year(s) ago
View a selection of this year’s shortlist featuring the most awe-inspiring astronomy photography from around the world
Source: www.rmg.co.ukCategories: Latest Headlines, RheumatologyTweet-
Have a look at the photos from the Astronomy Photo of the year competition. Pretty amazing photos https://t.co/imVxUNWpLb H/t @Nature https://t.co/EP5byczLx2
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Mashup Score: 0Characterising patterns of COVID-19 and long COVID symptoms: Evidence from nine UK longitudinal studies - 2 year(s) ago
Multiple studies across global populations have established the primary symptoms characterising COVID-19 (Coronavirus Disease 2019) and long COVID. However, as symptoms may also occur in the absence of COVID-19, a lack of appropriate controls has often meant that specificity of symptoms to acute COVID-19 or long COVID, and the extent and length of time for which they are elevated after COVID-19,…
Source: medRxivCategories: Latest Headlines, RheumatologyTweet-
Large Scale data on Long COVID from 42,000 people, 9 studies. https://t.co/ZwkQ6QworF https://t.co/2MxO9NPt1Q
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Mashup Score: 1The Solution Shop and the Production Line — The Case for a Frameshift for Physician Practices | NEJM - 2 year(s) ago
Perspective from The New England Journal of Medicine — The Solution Shop and the Production Line — The Case for a Frameshift for Physician Practices
Source: New England Journal of MedicineCategories: Latest Headlines, RheumatologyTweet-
The Solution Shop and the Production Line — The Case for a Frameshift for Physician Practices | NEJM https://t.co/40gJZHFs6G
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Mashup Score: 31A strategy that gives half of the world a discount on COVID-19 antivirals, but keeps a firm grip on power - Speaking of Medicine and Health - 2 year(s) ago
More than two years into a pandemic that has killed 15 million people, it seems we have learned nothing. When COVID-19 vaccines…
Source: Speaking of Medicine and HealthCategories: Latest Headlines, RheumatologyTweet-
RT @mellabarb: I wrote about the future of #COVID19 antiviral access in LMICs for @PLOSGPH https://t.co/lkxXXO15Eb
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Mashup Score: 0
Biomarker analysis of the phase 4 R4RA trial identifies pretreatment synovial biopsy features selectively associated with response to rituximab or tocilizumab, and leads to the development of models that might predict treatment benefit in patients with rheumatoid arthritis
Source: NatureCategories: Latest Headlines, RheumatologyTweet-
Follow-up on the toci vs rituximab trial: machine learning algorithms predictive of response to rituximab (AUC = 0.74, tocilizumab (AUC = 0.68) and, notably, multidrug resistance (AUC = 0.69) from @NatureMedicine https://t.co/brb9ND51da
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Mashup Score: 2Any Given Monday: Association Between Desk Rejections and Weekend Manuscript Submissions to Rheumatology Journals - 2 year(s) ago
Academic rheumatologists make substantial efforts to avoid “desk rejections,” where editors of rheumatology journals reject or transfer a manuscript prior to external peer review. Conventional strategies include a focus on novel or engaging content, the crafting of a compelling and answerable research question, involvement of collaborators with content expertise, rigorous study design and…
Source: The Journal of RheumatologyCategories: Latest Headlines, RheumatologyTweet-
This is pure gold @EBRheum @JointMD @jeffsparks @BolekBerqui Highly Recommended Read 😃 Any Given Monday: Association Between Desk Rejections and Weekend Manuscript Submissions to Rheumatology Journals @jrheum https://t.co/6t0G5X6Yst
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Mashup Score: 0Adult Evans' Syndrome - PubMed - 2 year(s) ago
Evans syndrome (ES) is a rare immune disorder defined as the simultaneous or sequential occurrence in a single patient of immune thrombocytopenia (ITP) and warm autoimmune hemolytic anemia (wAIHA) ± autoimmune neutropenia (AIN). ES represents approximately 5% to 10% of all wAIHA and 2%-5% of all ITP …
Source: PubMedCategories: Latest Headlines, RheumatologyTweet-
I have a patient with Evan’s syndrome & rheumatoid, and I found this review published last month but my library doesn’t subscribe to this journal 😔. Anyone’s library subscribe to Haem/Onc Clinics of North America? Adult Evans' Syndrome - PubMed https://t.co/YBXat0zz4Y
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Mashup Score: 0Efficacy and safety of mavrilimumab in giant cell arteritis: a phase 2, randomised, double-blind, placebo-controlled trial - 2 year(s) ago
Objectives Granulocyte-macrophage colony-stimulating factor (GM-CSF) is implicated in pathogenesis of giant cell arteritis. We evaluated the efficacy of the GM-CSF receptor antagonist mavrilimumab in maintaining disease remission. Methods This phase 2, double-blind, placebo-controlled trial enrolled patients with biopsy-confirmed or imaging-confirmed giant cell arteritis in 50 centres (North…
Source: Annals of the Rheumatic DiseasesCategories: Latest Headlines, RheumatologyTweet-
So this looks interesting => Efficacy and safety of mavrilimumab in giant cell arteritis. Anyone know about a phase 3? @LCalabreseDO @CCalabreseDO @drdavidliew @SattuiSEMD @EBRheum @Sarah_L_Mackie https://t.co/4PhqZ0gtdL
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Mashup Score: 0Tocilizumab in patients with new onset polymyalgia rheumatica (PMR-SPARE): a phase 2/3 randomised controlled trial - 2 year(s) ago
Background Polymyalgia rheumatica is the second most common inflammatory rheumatic disease of people >50 years. Glucocorticoid therapy is highly effective, but many patients require treatment for several years. Effective glucocorticoid sparing agents are still needed. Methods In this double-blind, multi-centre phase 2/3 clinical trial, we randomly assigned 36 patients with new onset polymyalgia…
Source: Annals of the Rheumatic DiseasesCategories: Latest Headlines, RheumatologyTweet-
I have done this on a number of occasions and it has been very successful (eg. Psychosis with steroids); the tough part is convincing payers that the cost of the Actemra outweighs the overall adverse steroid events - need to take into account all AEs https://t.co/09pfSlXhFH
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This has the potential to drastically reduce morbidity and mortality from CKD. Clinical trials for pig-to-human organ transplants inch closer. https://t.co/wJegcTLyOt