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Mashup Score: 1Spatial single-cell protein landscape reveals vimentinhigh macrophages as immune-suppressive in the microenvironment of hepatocellular carcinoma - 1 month(s) ago
Nature Cancer – Qui et al. perform co-detection by indexing profiling of 401 hepatocellular carcinoma patient samples and identify a role for vimentinhigh macrophages in instructing an…
Source: www.nature.comCategories: General Medicine News, Oncologists1Tweet
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Mashup Score: 3Spatial single-cell protein landscape reveals vimentinhigh macrophages as immune-suppressive in the microenvironment of hepatocellular carcinoma - 1 month(s) ago
Nature Cancer – Qui et al. perform co-detection by indexing profiling of 401 hepatocellular carcinoma patient samples and identify a role for vimentinhigh macrophages in instructing an…
Source: www.nature.comCategories: General Medicine News, Oncologists1Tweet-
Online now - Resource "Spatial single-cell protein landscape reveals vimentin-high macrophages as immune-suppressive in the microenvironment of hepatocellular carcinoma" by @LabDfelsher & Renumathy Dhanasekaran đź”—https://t.co/TtOtFLu78L
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Mashup Score: 20ISB 2001 trispecific T cell engager shows strong tumor cytotoxicity and overcomes immune escape mechanisms of multiple myeloma cells - 1 month(s) ago
Nature Cancer – Perro and colleagues develop a CD3+ T cell engager co-targeting BCMA and CD38 to improve immunotherapy for multiple myeloma, demonstrate cytotoxicity in patient-derived samples and…
Source: www.nature.comCategories: General Medicine News, Oncologists1Tweet-
Mario Perro & colleagues develop a CD3+ T cell engager co-targeting BCMA and CD38 to improve immunotherapy for multiple myeloma, demonstrate cytotoxicity in patient-derived samples and murine models and develop a quantitative systems pharmacology model đź”—https://t.co/DBJv2zXiXu
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Mashup Score: 8Defining and defeating metastasis - 1 month(s) ago
Late registration is still available. Please reach out to events@embl.org to request it. This conference will take place at EMBL Heidelberg, with the option to attend virtually. In its second edition, this symposium will cover emerging key concepts of latent metastasis and dissemination of tumour cells including evolution and genetic diversity of metastasis, circulating tumour cells, stemness, dormancy and stromal reprogramming, transcriptional and epigenetic control, motility and invasive signalling,
Source: www.embl.orgCategories: General Medicine News, Oncologists1Tweet-
Our Associate Editor Julieta Alfonso is looking forward to attending the EMBO-EMBL symposium in Heidelberg. Reach out if you want to discuss your science or publishing in @NatureCancer- or find Julieta at the 'Meet-the-Editor' panel on Oct 1st. https://t.co/KhVJ0PKHDi
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Mashup Score: 238A protein expression atlas on tissue samples and cell lines from cancer patients provides insights into tumor heterogeneity and dependencies - 2 month(s) ago
Nature Cancer – Liang and colleagues establish a high-quality protein expression resource for 8,000 The Cancer Genome Atlas patient samples and 900 Cancer Cell Line Encyclopedia cell lines for…
Source: www.nature.comCategories: General Medicine News, Oncologists1Tweet-
NEW CONTENT @NatureCancer 'A protein expression atlas on tissue samples and cell lines from cancer patients provides insights into tumor heterogeneity and dependencies' by Akbani, Mills, Liang and collaborators https://t.co/w5O4xuKVnD
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Mashup Score: 14A targetable type III immune response with increase of IL-17A expressing CD4+ T cells is associated with immunotherapy-induced toxicity in melanoma - 2 month(s) ago
Nature Cancer – Dimitriou et al. perform multiomic profiling of patients with melanoma experiencing immunotherapy-associated toxicity and identify a targetable role for type III-associated immune…
Source: www.nature.comCategories: General Medicine News, Oncologists1Tweet-
NOW ONLINE @NatureCancer 'A targetable type III immune response with increase of IL-17A expressing CD4+ T cells is associated with immunotherapy-induced toxicity in melanoma' ✏️By Florentia Dimitriou, Reinhard Dummer and co-authors https://t.co/eqHI9he8Eg
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Mashup Score: 13BRD-810 is a highly selective MCL1 inhibitor with optimized in vivo clearance and robust efficacy in solid and hematological tumor models - 3 month(s) ago
Nature Cancer – Rauh et al. developed a selective MCL1 inhibitor that is efficacious in hematological and solid tumors and has the advantage of limited cardiotoxicity because of more rapid…
Source: www.nature.comCategories: General Medicine News, Oncologists1Tweet-
🔔New Article ONLINE Ulrike Rauh & Todd Golub and colleagues developed a selective MCL1 inhibitor that is efficacious in hematological and solid tumors and that limits cardiotoxicity via a more rapid clearance of the drug in vivo. 👇 https://t.co/gwpbCfmv7j
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Mashup Score: 6The microbiome in cancer immunotherapy - 3 month(s) ago
The microbiota can influence the immune system and modulate response to cancer immunotherapy. In this webinar, our speakers will introduc…
Source: cassyni.comCategories: General Medicine News, Oncologists1Tweet-
Save the date! @NatureCancer and @NatureComms are hosting the webinar "The #microbiome in #cancer #immunotherapy" with Laurence Zitvogel @nsegata @tsonipeled @maria_rescigno 📅 Wednesday 18th Sep 2024 ⏰ 10 am ET / 3 pm UK time https://t.co/cZ2mpEE9wB
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Mashup Score: 75Integrative single-cell analysis of human colorectal cancer reveals patient stratification with distinct immune evasion mechanisms - 3 month(s) ago
Nature Cancer – Cheng and colleagues performed an integrative analysis of human colorectal cancer samples to characterize the tumor microenvironment (TME) and stratify patients according to their…
Source: www.nature.comCategories: General Medicine News, Oncologists1Tweet-
đź””Now Online - Analysis Integrative single-cell analysis of human colorectal cancer reveals patient stratification with distinct immune evasion mechanisms by @ZeminZhangLab & Sijin Cheng and colleagues https://t.co/xUEdoRNDki
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Mashup Score: 44Co-targeting SOS1 enhances the antitumor effects of KRASG12C inhibitors by addressing intrinsic and acquired resistance - 3 month(s) ago
Nature Cancer – Hofmann and colleagues describe the mechanism underlying the therapeutic benefit of combinatorial use of SOS1 and KRAS-G12C inhibitors in the context of KRAS-G12C mutant-driven lung…
Source: www.nature.comCategories: General Medicine News, Oncologists1Tweet-
đź””NOW ONLINE! Research article @NatureCancer from Marco Hofmann, Venu Thatikonda and colleagues on targeting SOS1 to enhance the antitumor effects of KRAS-G12C inhibitors by tackling intrinsic and acquired resistance. Read it here: đź”—https://t.co/sCYlnx8yWw
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Online now - Resource "Spatial single-cell protein landscape reveals vimentin-high macrophages as immune-suppressive in the microenvironment of hepatocellular carcinoma" by @LabDfelsher & Renumathy Dhanasekaran đź”—https://t.co/TtOtFLu78L