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Mashup Score: 525Pathological consequences of DNA damage in the kidney - 3 month(s) ago
Nature Reviews Nephrology – The DNA damage response is essential to genomic stability. Here, the authors discuss DNA damage-induced nephrotoxicity and kidney cancer, and the essential role of DNA…
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Mashup Score: 206Regulated cell death pathways in kidney disease - 3 month(s) ago
Nature Reviews Nephrology – Pathways of regulated cell death may contribute to the pathogenesis of various kidney diseases. Here, the authors provide an overview of the relationship between…
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Mashup Score: 159Regulation of FGF23 production and phosphate metabolism by bone–kidney interactions - 3 month(s) ago
Nature Reviews Nephrology – In this Review, the authors discuss the mineral-related factors and kidney-derived molecules that regulate osteocyte FGF23 production in health and disease. They also…
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Mashup Score: 18Youth-onset type 2 diabetes mellitus: an urgent challenge - 3 month(s) ago
Nature Reviews Nephrology – This Review describes the global epidemiology, clinical course and key complications of youth-onset type 2 diabetes mellitus. The authors also discuss the mechanisms…
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Mashup Score: 85Cisplatin nephrotoxicity: new insights and therapeutic implications - 3 month(s) ago
Nature Reviews Nephrology – Here, the authors review the mechanisms that underlie cisplatin-induced acute kidney injury and chronic kidney disease. They also discuss the challenges of developing…
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Mashup Score: 101The role of immune cells and mediators in preeclampsia - 4 month(s) ago
Nature Reviews Nephrology – Immune dysregulation contributes to the pathogenesis of preeclampsia. Here, the authors examine the role of immune cells and mediators in driving the oxidative stress…
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Mashup Score: 154Cellular senescence: the good, the bad and the unknown - 4 month(s) ago
Nature Reviews Nephrology – Cellular senescence has beneficial functions in embryonic development, wound healing and tumour suppression but can also be maladaptive, contributing to cancer…
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Mashup Score: 47Biomolecular condensates in kidney physiology and disease - 4 month(s) ago
Nature Reviews Nephrology – Biomolecular condensates are membraneless compartments that typically contain proteins and RNAs and broadly affect many cell types and organs. In the kidney in…
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Mashup Score: 8A new era in the science and care of kidney diseases - 4 month(s) ago
Nature Reviews Nephrology – Despite notable progress in basic, clinical and translational nephrology research in the past 50 years, many challenges remain. In this Review, the authors provide an…
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Mashup Score: 9
Nature Reviews Nephrology – Renal cell carcinoma is a metabolic disease linked to a variety of alterations in genes that regulate cellular metabolism. Here, the authors examine cell-intrinsic…
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An overview of DNA damage repair pathways. https://t.co/N4A6GqAz8U https://t.co/1B1RrzRAov