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Mashup Score: 0Daniel Steinfort and Shankar Siva on radiotherapy field planning in patients with NSCLC - The Lancet Respiratory Medicine in conversation with - 1 month(s) ago
Professor Daniel Steinfort and Professor Shankar Siva discuss the effect of systematic endoscopic mediastinal staging on radiotherapy field planning in patients with locally advanced non-small-cell lung cancer.
Categories: General Medicine News, PulmonologyTweet
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Mashup Score: 0A Monument to the Past - 1 month(s) ago
Abastumani Tuberculosis Hospital began life as a small wooden palace, high in the Caucasus Mountains, surrounded by pine trees and mist. It was built in the late nineteenth century for Grand Prince Georgi Romanov (1871â1899), younger brother of Nikolai II (1868â1918), the last of the Russian Tsars. Georgi had been plagued by respiratory problems since early childhood. After he started coughing up blood, his physicians decided he would be better off in the clean, dry air of Abastumani, in modern day Georgia.
Source: www.thelancet.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 13Ending tuberculosis: ways forward - 2 month(s) ago
Around 25â000 people die from tuberculosis every week, despite the disease being curable. Progress in reducing tuberculosis morbidity and mortality is hindered by inadequate access to testing and treatment, with at least 40% of those infected remaining undiagnosed. Our 2022 Series, highlighted the huge scale of the problem, exacerbated by COVID-19, and outlined priorities for rapid restoration of tuberculosis services. In a 2023 Editorial, we discussed the need for substantial investment in vaccines and research to improve health-care services in LMICs.
Source: www.thelancet.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 13Ending tuberculosis: ways forward - 2 month(s) ago
Around 25â000 people die from tuberculosis every week, despite the disease being curable. Progress in reducing tuberculosis morbidity and mortality is hindered by inadequate access to testing and treatment, with at least 40% of those infected remaining undiagnosed. Our 2022 Series, highlighted the huge scale of the problem, exacerbated by COVID-19, and outlined priorities for rapid restoration of tuberculosis services. In a 2023 Editorial, we discussed the need for substantial investment in vaccines and research to improve health-care services in LMICs.
Source: www.thelancet.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 1âYes! We can end TB,â but remember the sequelae in children - 2 month(s) ago
As we mark World Tuberculosis Day on March 24, 2024, under the theme of âYes! We can end [tuberculosis] TBâ, we need to remember that achieving zero cases and deaths is only one aspect of the battle against this tenacious disease.1 To combat tuberculosis effectively, we need a more comprehensive approach that includes every stage of the journey, from pretreatment to life after tuberculosis.2 This continuum of care, which incorporates post-tuberculosis assessment and care (figure), is essential to ensure that those with a history of tuberculosis, especially children and adolescents, can thrive without having debilitating sequelae.
Source: www.thelancet.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 33Classification of early tuberculosis states to guide research for improved care and prevention: an international Delphi consensus exercise - 2 month(s) ago
The current activeâlatent paradigm of tuberculosis largely neglects the documented spectrum of disease. Inconsistency with regard to definitions, terminology, and diagnostic criteria for different tuberculosis states has limited the progress in research and product development that are needed to achieve tuberculosis elimination. We aimed to develop a new framework of classification for tuberculosis that accommodates key disease states but is sufficiently simple to support pragmatic research and implementation.
Source: www.thelancet.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 13Genetic factors for ILDâthe path of precision medicine - 2 month(s) ago
With increasing awareness of genetic factors and variants involved in the pathogenesis of interstitial lung diseases (ILDs) and expanded availability of genetic testing, pulmonologists diagnosing and managing ILD should appreciate their clinical significance. In patients with a family health history of a similar or the same disease, the term genetic is used to imply one or more underlying genetic components to be causative of the disease with a pathogenic variant. There is a need to use terms precisely and associate pathogenic variants with the specific ILD diagnosis.
Source: www.thelancet.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 21Reframing sepsis immunobiology for translation: towards informative subtyping and targeted immunomodulatory therapies - 2 month(s) ago
Sepsis is a common and deadly condition. Within the current model of sepsis immunobiology, the framing of dysregulated host immune responses into proinflammatory and immunosuppressive responses for the testing of novel treatments has not resulted in successful immunomodulatory therapies. Thus, the recent focus has been to parse observable heterogeneity into subtypes of sepsis to enable personalised immunomodulation. In this Personal View, we highlight that many fundamental immunological concepts such as resistance, disease tolerance, resilience, resolution, and repair are not incorporated into the current sepsis immunobiology model.
Source: www.thelancet.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 21A tobacco-free generation: the end goal of the endgame - 3 month(s) ago
Last year The Lancet Respiratory Medicine published an Editorial discussing how the tobacco endgame initiative could best establish a tobacco-free generation, in which less than 5% of the European population uses tobacco by 2040. A major goal to achieve this initiative will be to ensure that children and adolescents receive adequate help to avoid tobacco-related and nicotine-related products, in particular electronic nicotine delivery systems which are highly addictive.
Source: www.thelancet.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 0Tuberculosis, conflict, and displacement - 3 month(s) ago
In places where conflict and displacement are a constant threat, MĂ©decins Sans FrontiĂšres (MSF) has a straightforward way of ensuring that the people being treated for tuberculosis do not leave without their medication. MSF keeps a stock of so-called runaway kits containing sufficient drugs for each patient to finish their course. âIf it seems likely that people are going to be displaced, we hand out the kitsâ, Animesh Sinha (HIV/TB/Hepatitis Advisor, MSF, London, UK) told The Lancet Respiratory Medicine.
Source: www.thelancet.comCategories: General Medicine News, PulmonologyTweet
PODCAST: Daniel Steinfort and @_ShankarSiva join us to discuss the effect of systematic endoscopic mediastinal staging on radiotherapy field planning in patients with locally advanced NSCLC đListen here: https://t.co/nItGFazmu6 đ°Read Article here: https://t.co/7ndOf5Xhex https://t.co/gmCK37PsMI