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Mashup Score: 16Chemotherapy and Osimertinib Combination Should Be the First-Line Treatment for All Advanced EGFR+ NSCLC - 2 month(s) ago
“Don’t be afraid to give up the good to go for the great.”John D. Rockefeller
Source: www.jto.orgCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 1Five-Year Survival Outcomes After Carbon-Ion Radiotherapy for Operable Stage I NSCLC: A Japanese National Registry Study (J-CROS-LUNG) - 2 month(s) ago
The standard therapy for stage I NSCLC is surgery, but some operable patients refuse this option and instead undergo radiotherapy. Carbon-ion radiotherapy (CIRT) is a type of radiotherapy. The Japanese prospective nationwide registry study on CIRT began in 2016. Here, we analyzed real-world clinical outcomes of CIRT for operable patients with stage I NSCLC.
Source: www.jto.orgCategories: General Medicine News, Onc News and JournalsTweet-
The Japanese prospective nationwide registry study on CIRT, which began in 2016, studied real-world clinical outcomes of CIRT for operable pts w/stage I #NSCLC. The authors found that this treatment method has favorable outcomes w/tolerable toxicity. https://t.co/YDiOqrArWu #LCSM https://t.co/zR4WimunxM
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Mashup Score: 3
Extensive-stage small cell lung cancer (ES-SCLC) prognosis remains poor. The phase 3 RATIONALE-312 study aimed to evaluate efficacy and safety of tislelizumab plus chemotherapy as first-line treatment for ES-SCLC.
Source: www.jto.orgCategories: General Medicine News, Onc News and JournalsTweet-
In the phase 3 RATIONALE-312 study, researchers evaluated efficacy & safety of tislelizumab + chemo as first-line treatment for ES-SCLC. This treatment demonstrated statistically significant clinical benefit & manageable safety compared to placebo + chemo. https://t.co/KTi0h1QtjO https://t.co/8RnVhK23s2
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Mashup Score: 1Lung Cancer in Switzerland - 2 month(s) ago
Currently, 8.7 million people live in Switzerland—a number that has more than doubled in the past 100 years. In the same time, the population has become significantly older, and today, one-fifth is beyond retirement age (65 y in Switzerland). With an average life expectancy of 82 years in men and 86 years in women, Switzerland has one of the highest life expectancies worldwide.1 Annually, 43,000 people are diagnosed with having cancer in Switzerland. The estimated age-standardized lung cancer incidence in Switzerland is lower than that in surrounding countries (Fig. 1).
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Mashup Score: 4
This study analyzed all metastatic categories of the current tumor, node, and metastasis (TNM) classification of non-small cell lung cancer to propose modifications of the M component in the next edition (9th) of the classification.
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This study analyzed all metastatic categories of the TNM classification of #NSCLC to propose modifications of the M component in the 9th edition, the data validates the 8th edition M1a & M1b categories. Read more including a proposal re: the M1c category: https://t.co/YyN6PyDF4z https://t.co/4ch3qq5ks3
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Mashup Score: 3
There has been increasing interest in the risk of lung cancer related to rheumatoid arthritis (RA). We investigated the association between RA and the risk of lung cancer with consideration of key confounding factors, including RA serostatus and smoking status.
Source: www.jto.orgCategories: General Medicine News, Onc News and JournalsTweet-
A study investigates the association between rheumatoid arthritis & the risk of #lungcancer w/consideration of key confounding factors, incl. RA serostatus & smoking status. Pts w/RA showed increased risk of lung cancer compared to the group w/o RA. https://t.co/wSDS5gwetk #LCSM https://t.co/iQHxBuohl8
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Mashup Score: 3
The International Association for the Study of Lung Cancer (IASLC) collaborated with the International Mesothelioma Interest Group to propose the first tumor, node, and metastasis (TNM) stage classification system for diffuse pleural mesothelioma in 1995, accepted by the Union for International Cancer Control and the American Joint Committee on Cancer for the 6th and 7th edition stage classification manuals. The IASLC Staging and Prognostic Factors Committee Mesothelioma Domain developed and analyzed an international registry of patients with pleural mesothelioma and updated TNM descriptors for the 8th edition of the stage classification system.
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Four separate manuscripts on T, N, M, & stage groupings submitted to JTO summarize analyses of this data & will serve as the primary source of the proposed changes to the upcoming 9th edition of the pleural mesothelioma stage classification system. https://t.co/6p2YT606ie #LCSM https://t.co/CBCFnkQVHw
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Mashup Score: 12Current and Future Perspectives on CT Screening for Lung Cancer: A Road Map for 2023-2027 from the IASLC - 4 month(s) ago
Low-dose computed tomography (LDCT) screening for lung cancer significantly reduces mortality from lung cancer, as demonstrated in randomized controlled trials and meta-analyses. This review is based on the ninth CT screening symposium of the International Association for the Study of Lung Cancer (IASLC) which focuses on the major themes pertinent to the successful global implementation of LDCT screening and developed a strategy to further the implementation of lung cancer screening globally.These recommendations provide a 5-year road map to advance the implementation of LDCT screening globally including: (i) establishing universal screening program quality indicators; (ii) establishing evidence-based criteria to identify individuals who have never smoked but are at high risk of developing lung cancer; (iii) develop recommendations for incidentally detected lung nodule tracking and management protocols to complement programmatic lung cancer screening; (iv) Integrate artificial intellig
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Mashup Score: 9
Stage classification is an important underpinning of management in patients with cancer, and rests on a combination of three components: T for tumor extent, N for nodal involvement, and M for distant metastases. This article details the revision of the N and the M components of thymic epithelial tumors for the 9th edition of the TNM classification of malignant tumors proposed by the Thymic Domain of the International Association for the Study of Lung Cancer Staging and Prognostic Factors Committee.
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Mashup Score: 12Current and Future Perspectives on CT Screening for Lung Cancer: A Road Map for 2023-2027 from the IASLC - 5 month(s) ago
Low-dose computed tomography (LDCT) screening for lung cancer significantly reduces mortality from lung cancer, as demonstrated in randomized controlled trials and meta-analyses. This review is based on the ninth CT screening symposium of the International Association for the Study of Lung Cancer (IASLC) which focuses on the major themes pertinent to the successful global implementation of LDCT screening and developed a strategy to further the implementation of lung cancer screening globally.These recommendations provide a 5-year road map to advance the implementation of LDCT screening globally including: (i) establishing universal screening program quality indicators; (ii) establishing evidence-based criteria to identify individuals who have never smoked but are at high risk of developing lung cancer; (iii) develop recommendations for incidentally detected lung nodule tracking and management protocols to complement programmatic lung cancer screening; (iv) Integrate artificial intellig
Source: www.jto.orgCategories: General Medicine News, Onc News and JournalsTweet
Controversies in #LungCancer: Read why some researchers and clinicians believe that the combination of chemotherapy and osimertinib should be the first-line treatment for all advanced #EGFR+ #NSCLC. https://t.co/pLn5KqKAgi #LCSM https://t.co/F89P7hLnpO