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Mashup Score: 7
This cohort study examines the role of comprehensive bridging radiotherapy in the setting of chimeric antigen receptor T-cell therapy for non-Hodgkin lymphoma.
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Mashup Score: 3The State of State Biomarker Testing Insurance Coverage Laws - 4 hour(s) ago
This Viewpoint discusses laws mandating insurance coverage of biomarker testing to broaden access to care for patients with cancer.
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Mashup Score: 0PhALLCON Soars to New Heights—Faster, Stronger, but Better? - 7 hour(s) ago
In this issue of JAMA, Jabbour and colleagues1 report results from the interim analysis of the PhALLCON randomized trial with ponatinib vs imatinib, combined with reduced-intensity chemotherapy. They found ponatinib to have superior efficacy and a comparable safety profile for frontline treatment of…
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Mashup Score: 13
This randomized trial assesses the effect of ponatinib vs imatinib combined with low-intensity chemotherapy on disease remission in adults with newly diagnosed Philadelphia chromosome–positive acute lymphoblastic leukemia (ALL).
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Mashup Score: 8Decentralized Clinical Trials as a New Paradigm of Trial Delivery to Improve Equity of Access - 10 hour(s) ago
This clinical care review summarizes government policies for the safe conduct of clinical trials using the telehealth and decentralized clinical trials digital health models.
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Mashup Score: 33
This cohort study uses registry data to examine the risk of colorectal cancer (CRC) and CRC-specific death for up to 20 years after having a first colonoscopy with findings negative for CRC.
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Mashup Score: 21
This study of 5-year follow-up data from a phase 2 clinical trial examines the association of response with 12 induction instillations of bacillus Calmette-Guèrin (BCG) without maintenance therapy for patients with high-risk non–muscle-invasive bladder cancer (NMIBC).
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Mashup Score: 54
This review assesses current evidence and emerging treatment strategies for improved survival among patients with metastatic hormone-sensitive prostate cancer and offers recommendations for clinical practice application.
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Mashup Score: 3Association of Skin Microbiome Dynamics With Radiodermatitis in Patients With Breast Cancer - 2 day(s) ago
This observational study assesses the association of skin microbiome baseline composition and dynamics with the severity of radiodermatitis in patients undergoing adjuvant radiotherapy for breast cancer treatment.
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Mashup Score: 15Dose-Adjusted EPOCH Plus Inotuzumab Ozogamicin for Adult Relapsed or Refractory B-Cell ALL - 2 day(s) ago
This phase 1 dose-escalation trial examines whether inotuzumab ozogamicin plus dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin (EPOCH) is safe and effective for adults with relapsed or refractory B-cell acute lymphoblastic leukemia or lymphoma (ALL).
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Study reports higher sustained complete response, lower local relapse, & improved relapse- & event-free survivals in non-Hodgkin lymphoma pts w/ <5 pre-CART disease sites who received comprehensive bridging radiation vs. no bridging radiation. @OmranSaifi https://t.co/XWG1pgpoCN