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Mashup Score: 10Quality Improvement Intervention for Reducing Acute Treatment Times in Ischemic Stroke - 10 day(s) ago
This cluster randomized clinical trial examines data for patients with ischemic stroke who underwent endovascular thrombectomy before and after the hospitals implemented a performance-feedback dashboard designed to improve treatment times.
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 0Discontinuation of First-Line Disease-Modifying Therapy in Patients With Stable Multiple Sclerosis - 12 day(s) ago
This randomized clinical trial investigates whether first-line disease-modifying therapy can be safely discontinued in patients with long-term stable multiple sclerosis.
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet-
Most viewed in the last 7 days from @JAMANeuro: First-line disease-modifying therapy discontinuation can lead to recurrence of inflammatory disease activity in approximately 20% of cases, even in patients with long-term stable MS. https://t.co/ruHUR7GpSO https://t.co/wDyZrLv96h
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Mashup Score: 4Skin Biopsies vs CSF in the Diagnosis of Prion Diseases - 13 day(s) ago
This diagnostic study evaluates the ability of multiple skin biopsies to detect prion seeding activity compared with the cerebrospinal fluid (CSF) as a diagnostic biomarker in prion diseases.
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet-
The sensitivity of an real-time quaking-induced conversion analysis of a combination of 2 or more skin sites was superior to that of cerebrospinal fluid in diagnosing prion diseases. https://t.co/OC7GIM0fpY https://t.co/rUhk3abxGv
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Mashup Score: 5Disease Severity Staging System for NOTCH3-Associated Small Vessel Disease, Including CADASIL - 14 day(s) ago
This cohort study designed a disease severity staging system to capture the broad clinicoradiological severity spectrum of NOTCH3-associated small vessel disease, including cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet-
Most viewed in the last 7 days from @JAMANeuro: The NOTCH3-small vessel disease (NOTCH3-SVD) staging system captures the full disease severity spectrum associated with CADASIL-type NOTCH3 variants. https://t.co/LeIATCMgcb https://t.co/yH9EZA4mNP
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Mashup Score: 19Mobile Stroke Unit Management After Acute Ischemic Stroke - 14 day(s) ago
This cohort study investigates if prehospital management in a mobile stroke unit compared with standard emergency medical services management reduces the level of global disability at hospital discharge in patients with ischemic stroke who are potentially eligible for intravenous thrombolysis.
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet-
Prehospital management in a mobile stroke unit for patients with acute ischemic stroke potentially eligible for intravenous thrombolysis is associated with reduced global disability at hospital discharge. https://t.co/N1NHsBlzEP https://t.co/6B0MXW9mbJ
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Mashup Score: 5The Patient Portal Messaging Crisis - 15 day(s) ago
This Viewpoint proposes strategies for improving patient portal–based communication.
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet-
Viewpoint: Electronic health records and patient portals have improved patient access and communication but has also increased workload and burnout among physicians. https://t.co/dqyGUcPmGj https://t.co/dSZ6tT2B0s
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Mashup Score: 25Neurological Pupil Index and Intracranial Hypertension in Patients With Acute Brain Injury - 16 day(s) ago
This secondary analysis of the ORANGE study evaluates whether an association exists between the Neurological Pupil Index and invasive intracranial pressure.
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet-
Repeated Neurological Pupil Index measurements were insufficient to replace invasive monitoring in patients with subarachnoid hemorrhage, traumatic brain injury, and intracerebral hemorrhage. https://t.co/QOeApqed6T @fabio_taccone https://t.co/c6LRB8FqdU
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Mashup Score: 23Discontinuation of First-Line Disease-Modifying Therapy in Patients With Stable Multiple Sclerosis - 17 day(s) ago
This randomized clinical trial investigates whether first-line disease-modifying therapy can be safely discontinued in patients with long-term stable multiple sclerosis.
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet-
In the DOT-MS trial, discontinuation of first-line disease-modifying therapy in patients aged 18 and older lead to recurrence of inflammation in ~20% of cases. https://t.co/zhm1X6uX3H @eefst https://t.co/ELebdO8GAt
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Mashup Score: 11The Nontrivial Ethics of Brain Biopsies for Research - 18 day(s) ago
This Viewpoint advocates for adapting and expanding informed consent protocols for brain biopsies for research purposes.
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet-
Viewpoint from @NeuroBioEthics and @MichaelOkun discusses the ethical considerations of collecting brain biopsies during deep brain stimulation (DBS) surgery. https://t.co/8WVSsjYoeY https://t.co/wR3Rt3wKCA
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Mashup Score: 19
This study discusses 4-repeat tau seeding in the skin of patients with progressive supranuclear palsy.
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet-
Study introduces a 4R-Tau seeding amplification assay (SAA) for skin biopsies. This assay could transform diagnostic approaches and patient stratification in clinical trials for parkinsonian disorders. https://t.co/HuE3Zdt3Dy https://t.co/KbSTRBx6ZZ
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Performance feedback provided through a dashboard used by local quality improvement teams reduced door-to–groin puncture time for endovascular thrombectomy. https://t.co/uK9mJp5oI4 https://t.co/uZWCBXVwhJ