-
Mashup Score: 69The Efficacy and Safety of Metastasis-directed Therapy in Patients with Prostate Cancer: A Systematic Review and Meta-analysis of Prospective Studies - 2 month(s) ago
Metastasis-directed therapy results in promising clinical outcomes and low rates of adverse events. It can be a valuable treatment option either for oligorecurrent patients wishing to avoid androgen deprivation therapy or as a treatment intensification method. Phase 3 trials are necessary.
Source: www.europeanurology.comCategories: General Medicine News, UrologyTweet
-
Mashup Score: 15A 23-Gene Prognostic Index Predicts Progression and Bacillus Calmette-Guérin Response in Non–muscle-invasive Bladder Cancer - 3 month(s) ago
Prediction of the clinical behavior of non–muscle-invasive bladder cancer (NMIBC) and responses to bacillus Calmette-Guérin (BCG) therapy remains a formidable challenge [1] despite valuable insights facilitated by recent high-throughput technologies [2–4]. To enhance NMIBC prognostication, we used deep learning for an analysis of long-term follow-up data (median 89.5 mo in the discovery cohort) to develop a prognostic index (PI) for NMIBC progression (Supplementary Figs. 1 and 2). Disease progression was defined as an increase in stage after relapse from either Ta or T1 to stage ≥T2.
Source: www.europeanurology.comCategories: General Medicine News, UrologyTweet
-
Mashup Score: 32Different Responses to Neoadjuvant Chemotherapy in Urothelial Carcinoma Molecular Subtypes - 3 month(s) ago
We observed different complete response rates and an independent association with survival in bladder cancer molecular subtypes for patients treated with neoadjuvant chemotherapy and radical cystectomy.
Source: www.europeanurology.comCategories: General Medicine News, UrologyTweet
-
Mashup Score: 4The Needle in the Haystack: The Presence of Castrate-resistant Prostate Cancer Cells in Hormone-naïve Prostate Cancer - 3 month(s) ago
The spectrum of disease in localised prostate cancer is broad, ranging from low to high risk, and is clinically reflected by a wide range of treatments, including active surveillance and intensive curative treatments achievable through surgery or radiotherapy with or without androgen deprivation therapy [1]. In contrast to localised prostate cancer, men diagnosed with metastases will inevitably develop resistance to therapy (metastatic castration-resistant prostate cancer [mCPRC]) and succumb to their disease [2] despite multiple and improved palliative treatment options for these patients.
Source: www.europeanurology.comCategories: General Medicine News, UrologyTweet
-
Mashup Score: 8
Robot-assisted periprostatic artificial urinary sphincter implantation is an efficient alternative to the open approach in men with neurogenic stress urinary incontinence, resulting in shorter operative times, less blood loss, fewer severe complications, and shorter length of hospital stay, with similar functional results and need for revision surgery.
Source: www.europeanurology.comCategories: General Medicine News, UrologyTweet
-
Mashup Score: 60The Efficacy and Safety of Metastasis-directed Therapy in Patients with Prostate Cancer: A Systematic Review and Meta-analysis of Prospective Studies - 3 month(s) ago
Metastasis-directed therapy results in promising clinical outcomes and low rates of adverse events. It can be a valuable treatment option either for oligorecurrent patients wishing to avoid androgen deprivation therapy or as a treatment intensification method. Phase 3 trials are necessary.
Source: www.europeanurology.comCategories: General Medicine News, UrologyTweet
-
Mashup Score: 10February 2024 | European Urology Highlights - 3 month(s) ago
A great mixture on the European Urology Podcast this month with AI and bladder cancer featuring in our highlight papers (details below). Co-hosts Declan Mur…
Source: www.youtube.comCategories: General Medicine News, UrologyTweet
-
Mashup Score: 56The Elusive Horizon: Biomarkers in Urothelial Carcinoma - 3 month(s) ago
Urinary tests for circulating tumor DNA have potential for accurate discrimination of bladder cancer from other common inflammatory processes. Efforts are still needed to determine whether these tests can differentiate between cancer and field cancerization and to demonstrate clinical benefit in prospective trials.
Source: www.europeanurology.comCategories: General Medicine News, UrologyTweet
-
Mashup Score: 51The Elusive Horizon: Biomarkers in Urothelial Carcinoma - 3 month(s) ago
Urinary tests for circulating tumor DNA have potential for accurate discrimination of bladder cancer from other common inflammatory processes. Efforts are still needed to determine whether these tests can differentiate between cancer and field cancerization and to demonstrate clinical benefit in prospective trials.
Source: www.europeanurology.comCategories: General Medicine News, UrologyTweet
-
Mashup Score: 50The Elusive Horizon: Biomarkers in Urothelial Carcinoma - 3 month(s) ago
Urinary tests for circulating tumor DNA have potential for accurate discrimination of bladder cancer from other common inflammatory processes. Efforts are still needed to determine whether these tests can differentiate between cancer and field cancerization and to demonstrate clinical benefit in prospective trials.
Source: www.europeanurology.comCategories: General Medicine News, UrologyTweet
The Efficacy and Safety of Metastasis-directed Therapy in Patients with Prostate Cancer: A Systematic Review and Meta-analysis of Prospective Studies https://t.co/ljpQ3KpjlS #UroSoMe #ProstateCancer https://t.co/tw8VBerUT4