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Mashup Score: 62Cheap blood test detects pancreatic cancer before it spreads - 10 day(s) ago
Nature – The deadly cancer is often not found until it has spread to other parts of the body.
Source: www.nature.comCategories: General Medicine News, Expert PicksTweet
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Mashup Score: 4388Long-term yogurt intake and colorectal cancer incidence subclassified by Bifidobacterium abundance in tumor - 10 day(s) ago
Evidence suggests a tumor-suppressive effect of the intake of yogurt, which typically contains Bifidobacterium. We hypothesized that long-term yogurt intake might be associated with colorectal canc…
Source: www.tandfonline.comCategories: General Medicine News, Expert PicksTweet-
A link between yogurt intake and reduced risk of colon cancer, from cohort of over 130,00 participants, with inverse relationship to Bifidobacterium in gut microbiome https://t.co/VB45cv9Oa6 open-access https://t.co/ut0jZnbKYN https://t.co/0GhCJqWIzp
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Mashup Score: 35Uncovering the role of sleep on human health - 10 day(s) ago
Nature Medicine – A large-scale, phenome-wide study enables a holistic view of the role of sleep on human health, highlighting its potential as a modifiable risk factor for chronic disease.
Source: www.nature.comCategories: General Medicine News, Future of MedicineTweet-
Good commentary today on this unique, comprehensive study of sleep and health https://t.co/6Txj3ZwlZp
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Mashup Score: 610Scratching promotes allergic inflammation and host defense via neurogenic mast cell activation - 11 day(s) ago
Itch is a dominant symptom in dermatitis, and scratching promotes cutaneous inflammation, thereby worsening disease. However, the mechanisms through which scratching exacerbates inflammation and whether scratching provides benefit to the host are largely …
Source: www.science.orgCategories: General Medicine News, Expert PicksTweet-
In @ScienceMagazine today, the discovery of the neuroimmune itch-scratch circuit. And why scratching can make things worse https://t.co/psn5XDuyD9 https://t.co/bq17rsEqwB https://t.co/zxJL9WHW1O
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Mashup Score: 278A potent epigenetic editor targeting human PCSK9 for durable reduction of low-density lipoprotein cholesterol levels - 11 day(s) ago
Nature Medicine – Epigenetic editing of PCSK9 in the liver, designed to induce DNA methylation and silence gene expression, achieved long-lasting reductions in LDL cholesterol levels in both…
Source: www.nature.comCategories: General Medicine News, Expert PicksTweet-
Most genome editing work to date has been DNA based. A new paper out today assessed a single dose of epigenetic editing (thru PCSK9) for marked (~70%) and durable reduction of LDL cholesterol [in non-human primates] https://t.co/W7gJX8Defm @NatureMedicine @jaffeab @chromamedicine https://t.co/2ajrrVcsrT
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Mashup Score: 138The Microplastic Concerns Elevate—To the Brain - 11 day(s) ago
A new study shows accumulation in the brain, much higher in people with dementia, and 7-30 times greater than other organs (liver and kidney).
Source: erictopol.substack.comCategories: General Medicine News, Expert PicksTweet-
Covered here, with relevant background and another new study on blood clots in the brain after microplastics https://t.co/15SGIx6rgL https://t.co/orIy82Tdmq
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Mashup Score: 270A potent epigenetic editor targeting human PCSK9 for durable reduction of low-density lipoprotein cholesterol levels - 12 day(s) ago
Nature Medicine – Epigenetic editing of PCSK9 in the liver, designed to induce DNA methylation and silence gene expression, achieved long-lasting reductions in LDL cholesterol levels in both…
Source: www.nature.comCategories: General Medicine News, Expert PicksTweet-
Most genome editing work to date has been DNA based. A new paper out today assessed a single dose of epigenetic editing (thru PCSK9) for marked (~70%) and durable reduction of LDL cholesterol [in non-human primates] https://t.co/W7gJX8Defm @NatureMedicine @jaffeab @chromamedicine https://t.co/2ajrrVcsrT
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Mashup Score: 34Gut microbiota-derived hexa-acylated lipopolysaccharides enhance cancer immunotherapy responses - 12 day(s) ago
Nature Microbiology – Hexa-acylated lipopolysaccharides from the gut microbiota are associated with efficacy in patients with cancer receiving anti-PD-1 and stimulate host immune activation for…
Source: www.nature.comCategories: General Medicine News, Expert PicksTweet-
Enhancing cancer immunotherapy response via gut microbiome manipulation. Metagenomics from patients who responded led to testing in implanted tumor mouse model to confirm effect https://t.co/B1nudbpXXH @NatureMicrobiol
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Mashup Score: 710Artificial intelligence for direct-to-physician reporting of ambulatory electrocardiography - 12 day(s) ago
Nature Medicine – In a large-scale analysis of ambulatory electrocardiographic recordings, a deep learning algorithm had a substantially higher sensitivity for the detection of critical arrhythmias…
Source: www.nature.comCategories: General Medicine News, Expert PicksTweet-
Getting your real-time heart rhythm monitored for 10 days now requires an ECG technician to review and notify your doctor of a critical arrhythmia. A new study showed A.I. did better than technicians (98.6% vs 80.3%) for identifying these abnormalities https://t.co/yhvLvRO09Q… https://t.co/qsRLmWie6I
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Mashup Score: 228
The move halts a large slice of money for most universities and research institutions virtually overnight, imperiling vital research in everything from cancer to heart disease.
Source: www.washingtonpost.comCategories: General Medicine News, Expert PicksTweet-
It's not "breaking news" now, since it was announced by NIH yesterday. But it is breaking....... https://t.co/k3aTR8SbyT https://t.co/JaySY1ZT4h
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A brief explainer here https://t.co/XBhvAeYkH9